Print ISSN: 2312-508X Online ISSN: 2312-5098 Print ISBN: 978-1-84984-083-5 Online ISBN: 978-1-84984-084-2 March 2017 €60.00 9 781849 840835 Anti-infectives and the Lung Edited by Stefano Aliberti, James D. Chalmers and Mathias W. Pletz ERS monograph 75 Pulmonary infections are a major cause of morbidity and mortality worldwide. Adequate and timely treatment of these infections is therefore of vital importance, especially when considering the emerging problem of antimicrobial resistance. This Monograph provides a comprehensive up-to-date overview of the use of anti-infectives in lung diseases, with chapters covering community- and hospital-acquired pneumonia, exacerbations of asthma and chronic obstructive pulmonary disease, tuberculosis and nontuberculous mycobacteria pulmonary disease, pleural infections, and fungal diseases. Other chapters address antibiotic stewardship in the community and hospital settings, and the use of antibiotics in specific patient groups (e.g. critically ill and paediatric patients). Mechanisms of action and resistance, diagnostic approaches, therapeutic options (e.g. combination therapy, dosing and routes of administration), and the development of new drugs are also discussed. Anti-infectives and the Lung ERS monograph ERS monograph Anti-infectives and the Lung Edited by Stefano Aliberti, James D. Chalmers and Mathias W. Pletz Editor in Chief Robert Bals This book is one in a series of ERS Monographs. Each individual issue provides a comprehensive overview of one specific clinical area of respiratory health, communicating information about the most advanced techniques and systems required for its investigation. It provides factual and useful scientific detail, drawing on specific case studies and looking into the diagnosis and management of individual patients. Previously published titles in this series are listed at the back of this Monograph. ERS Monographs are available online at www.erspublications.com and print copies are available from www.ersbookshop.com Continuing medical education (CME) credits are available through many issues of the ERS Monograph. Following evaluation, successful Monographs are accredited by the European Board for Accreditation in Pneumology (EBAP) for 5 CME credits. To earn CME credits, read the book of your choice (it is clearly indicated on the online table of contents whether CME credits are available) then complete the CME question form that is available at www.erseducation.org/e-learning/cme-tests.aspx Editorial Board: Antonio Anzueto (San Antonio, TX, USA), Leif Bjermer (Lund, Sweden), John R. Hurst (London, UK) and Carlos Robalo Cordeiro (Coimbra, Portugal). Managing Editors: Rachel White, Catherine Pumphrey and Ray Loughlin European Respiratory Society, 442 Glossop Road, Sheffield, S10 2PX, UK Tel: 44 114 2672860 | E-mail:
[email protected] Published by European Respiratory Society ©2017 March 2017 Print ISBN: 978-1-84984-083-5 Online ISBN: 978-1-84984-084-2 Print ISSN: 2312-508X Online ISSN: 2312-5098 Typesetting by Nova Techset Private Limited Printed by Ashford Colour Press Limited All material is copyright to European Respiratory Society. It may not be reproduced in any way including electronic means without the express permission of the company. Statements in the volume reflect the views of the authors, and not necessarily those of the European Respiratory Society, editors or publishers. This book contains drug dosage information. The dosages and regimens presented herein are drawn from the best available evidence at the time of writing, and the expertise and experience of the authors. However, they are necessarily illustrative and must