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Pharmaceutical Statistics
DRUGS AND THE PHARMACEUTICAL SCIENCES A Series of Textbooks and Monographs
Executive Editor James Swarbrick PharmaceuTech, Inc. Pinehurst, North Carolina
Advisory Board Larry L. Augsburger University of Maryland Baltimore, Maryland
Jennifer B. Dressman University of Frankfurt Institute of Pharmaceutical Technology Frankfurt, Germany
Harry G. Brittain Center for Pharmaceutical Physics Milford, New Jersey
Robert Gurny Universite de Geneve Geneve, Switzerland
Jeffrey A. Hughes Anthony J. Hickey University of North Carolina School of Pharmacy Chapel Hill, North Carolina
University of Florida College of Pharmacy Gainesville, Florida
Vincent H. L. Lee Ajaz Hussain Sandoz Princeton, New Jersey
Joseph W. Polli GlaxoSmithKline Research Triangle Park North Carolina
US FDA Center for Drug Evaluation and Research Los Angeles, California
Kinam Park Purdue University West Lafayette, Indiana
Jerome P. Skelly Stephen G. Schulman
Alexandria, Virginia
University of Florida Gainesville, Florida
Elizabeth M. Topp
Yuichi Sugiyama
University of Kansas Lawrence, Kansas
University of Tokyo, Tokyo, Japan
Peter York Geoffrey T. Tucker University of Sheffield Royal Hallamshire Hospital Sheffield, United Kingdom
University of Bradford School of Pharmacy Bradford, United Kingdom
For information on volumes 1–151 in the Drugs and Pharmaceutical Science Series, Please visit www.informahealthcare.com 152. Preclinical Drug Development, edited by Mark C. Rogge and David R. Taft 153. Pharmaceutical Stress Testing: Predicting Drug Degradation, edited by Steven W. Baertschi 154. Handbook of Pharmaceutical Granulation Technology: Second Edition, edited by Dilip M. Parikh 155. Percutaneous Absorption: Drugs–Cosmetics–Mechanisms–Methodology, Fourth Edition, edited by Robert L. Bronaugh and Howard I. Maibach 156. Pharmacogenomics: Second Edition, edited by Werner Kalow, Urs A. Meyer and Rachel F. Tyndale 157. Pharmaceutical Process Scale-Up, Second Edition, edited by Michael Levin 158. Microencapsulation: Methods and Industrial Applications, Second Edition, edited by Simon Benita 159. Nanoparticle Technology for Drug Delivery, edited by Ram B. Gupta and Uday B. Kompella 160. Spectroscopy of Pharmaceutical Solids, edited by Harry G. Brittain 161. Dose Optimization in Drug Development, edited by Rajesh Krishna 162. Herbal Supplements-Drug Interactions: Scientific and Regulatory Perspectives, edited by Y. W. Francis Lam, Shiew-Mei Huang, and Stephen D. Hall 163. Pharmaceutical Photostability and Stabilization Technology, edited by Joseph T. Piechocki and Karl Thoma 164. Environmental Monitoring for Cleanrooms and Controlled Environments, edited by Anne Marie Dixon 165. Pharmaceutical Product Development: In Vitro-ln Vivo Correlation, edited by Dakshina Murthy Chilukuri, Gangadhar Sunkara, and David Young 166. Nanoparticulate Drug Delivery Systems, edited by Deepak Thassu, Michel Deleers, and Yashwant Pathak 167. Endotoxins: Pyrogens, LAL Testing and Depyrogenation, Third Edition, edited by Kevin L. Williams 168. Good Laboratory Practice Regulations, Fourth Edition, edited by Anne Sandy Weinberg 169. Good Manufacturing Practices for Pharmaceuticals, Sixth Edition, edited by Joseph D. Nally 170. Oral-Lipid Based Formulations: Enhancing the Bioavailability of Poorly Water-soluble Drugs, edited by David J. Hauss 171. Handbook of Bioequivalence Testing, edited by Sarfaraz K. Niazi 172. Advanced Drug Formulation Design to Optimize Therapeutic Outcomes, edited by Robert O. Williams III, David R. Taft, and Jason T. McConville 173. Clean-in-Place for Biopharmaceutical Processes, edited by Dale A. Seiberling 174. Filtration and Purification in the Biopharmaceutical Industry, Second Edition, e