Molecular Virology

Susanne Modrow Dietrich Falke Uwe Truyen Hermann Schätzl Molecular Virology 1 3Reference Molecular Virology Susanne Modrow • Dietrich Falke Uwe Truyen • Hermann Sch€atzl Molecular Virology With 164 Figures and 86 Tables Susanne Modrow Institute of Medical Microbiology and Hygiene University of Regensburg Regensburg, Germany Uwe Truyen Institute for Animal Hygiene and Veterinary Public Health University of Leipzig Leipzig, Germany Dietrich Falke Institute of Virology Johannes Gutenberg University Mainz, Germany Hermann Sch€atzl Department of Comparative Biology & Experimental Medicine, Faculty of Veterinary Medicine, Faculty of Medicine University of Calgary Calgary, Canada Translation and Copyediting Ariel Quin˜ones Halle, Germany Dr. Stuart Evans West Rainton, UK ISBN 978-3-642-20717-4 ISBN 978-3-642-20718-1 (eBook) ISBN 978-3-642-20719-8 (print and electronic bundle) DOI 10.1007/978-3-642-20718-1 Springer Heidelberg New York Dordrecht London This work is based on the 3rd German language edition of Molekulare Virologie, by Susanne Modrow, Dietrich Falke, Uwe Truyen, Hermann Sch€atzl, published by Spektrum Akademischer Verlag, Heidelberg 2010. Library of Congress Control Number: 2013945856 # Springer-Verlag Berlin Heidelberg 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Preface Today, knowledge about viruses or distinct aspects of viral infections has become important for our daily life. Continuously, we are confronted with headlines and news concerning, e.g., new influenza viruses, outbreaks of n