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ABPP Methodology: Introduction and Overview, by Matthew B. Nodwell und Stephan A. Sieber Activity-Based Protein Profiling for Natural Product Target Discovery, by Joanna Krysiak und Rolf Breinbauer Photoaffinity Labeling in Activity-Based Protein Profiling, by Paul P. Geurink, Laurette M. Prely, Gijs A. van der Marel, Rainer Bischoff und Herman S. Overkleeft Application of Activity-Based Protein Profiling to the Study of Microbial Pathogenesis, by William P. Heal und Edward W. Tate Functional Analysis of Protein Targets by Metabolomic Approaches, by Yun-Gon Kim und Alan Saghatelian
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Topics in Current Chemistry
Editorial Board: K.N. Houk C.A. Hunter M.J. Krische J.-M. Lehn S.V. Ley M. Olivucci J. Thiem M. Venturi P. Vogel C.-H. Wong H. Wong H. Yamamoto l
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Activity-Based Protein Profiling
Volume Editor: Stephan A. Sieber
With Contributions by R. Breinbauer R. Bischoff P.P. Geurink W.P. Heal Y.-G. Kim J. Krysiak G.A. van der Marel M.B. Nodwell H.S. Overkleeft L.M. Prely A. Saghatelian S.A. Sieber E.W. Tate
Editor Prof. Dr. Stephan A. Sieber Department of Organic Chemistry II Technical University of Munich Garching Germany
ISSN 0340-1022 e-ISSN 1436-5049 ISBN 978-3-642-28377-2 e-ISBN 978-3-642-28378-9 DOI 10.1007/978-3-642-28378-9 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2012932058 # Springer-Verlag Berlin Heidelberg 2012 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtaine