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ABPP Methodology: Introduction and Overview, by Matthew B. Nodwell und Stephan A. Sieber Activity-Based Protein Profiling for Natural Product Target Discovery, by Joanna Krysiak und Rolf Breinbauer Photoaffinity Labeling in Activity-Based Protein Profiling, by Paul P. Geurink, Laurette M. Prely, Gijs A. van der Marel, Rainer Bischoff und Herman S. Overkleeft Application of Activity-Based Protein Profiling to the Study of Microbial Pathogenesis, by William P. Heal und Edward W. Tate Functional Analysis of Protein Targets by Metabolomic Approaches, by Yun-Gon Kim und Alan Saghatelian
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324 Topics in Current Chemistry Editorial Board: K.N. Houk C.A. Hunter M.J. Krische J.-M. Lehn S.V. Ley M. Olivucci J. Thiem M. Venturi P. Vogel C.-H. Wong H. Wong H. Yamamoto l l l l l l l l l Topics in Current Chemistry Recently Published and Forthcoming Volumes Activity-Based Protein Profiling Volume Editor: Stephan A. Sieber Vol. 324, 2012 Advanced X-Ray Crystallography Volume Editor: Kari Rissanen Vol. 315, 2012 Beauty in Chemistry Volume Editor: Luigi Fabbrizzi Vol. 323, 2012 Pyrethroids: From Chrysanthemum to Modern Industrial Insecticide Volume Editors: Noritada Matsuo, Tatsuya Mori Vol. 314, 2012 Constitutional Dynamic Chemistry Volume Editor: Mihail Barboiu Vol. 322, 2012 EPR Spectroscopy Volume Editors: Malte Drescher, Gunnar Jeschke Vol. 321, 2012 Radicals in Synthesis III Volume Editors: Markus R. Heinrich, Andreas Gansa¨uer Vol. 320, 2012 Chemistry of Nanocontainers Volume Editors: Markus Albrecht, F. Ekkehardt Hahn Vol. 319, 2012 Liquid Crystals: Materials Design and Self-Assembly Volume Editor: Carsten Tschierske Vol. 318, 2012 Fragment-Based Drug Discovery and X-Ray Crystallography Volume Editors: Thomas G. Davies, Marko Hyvo¨nen Vol. 317, 2012 Novel Sampling Approaches in Higher Dimensional NMR Volume Editors: Martin Billeter, Vladislav Orekhov Vol. 316, 2012 Unimolecular and Supramolecular Electronics II Volume Editor: Robert M. Metzger Vol. 313, 2012 Unimolecular and Supramolecular Electronics I Volume Editor: Robert M. Metzger Vol. 312, 2012 Bismuth-Mediated Organic Reactions Volume Editor: Thierry Ollevier Vol. 311, 2012 Peptide-Based Materials Volume Editor: Timothy Deming Vol. 310, 2012 Alkaloid Synthesis Volume Editor: Hans-Joachim Kno¨lker Vol. 309, 2012 Fluorous Chemistry Volume Editor: Istva´n T. Horva´th Vol. 308, 2012 Multiscale Molecular Methods in Applied Chemistry Volume Editors: Barbara Kirchner, Jadran Vrabec Vol. 307, 2012 Solid State NMR Volume Editor: Jerry C. C. Chan Vol. 306, 2012 Activity-Based Protein Profiling Volume Editor: Stephan A. Sieber With Contributions by R. Breinbauer R. Bischoff P.P. Geurink W.P. Heal Y.-G. Kim J. Krysiak G.A. van der Marel M.B. Nodwell H.S. Overkleeft L.M. Prely A. Saghatelian S.A. Sieber E.W. Tate Editor Prof. Dr. Stephan A. Sieber Department of Organic Chemistry II Technical University of Munich Garching Germany ISSN 0340-1022 e-ISSN 1436-5049 ISBN 978-3-642-28377-2 e-ISBN 978-3-642-28378-9 DOI 10.1007/978-3-642-28378-9 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2012932058 # Springer-Verlag Berlin Heidelberg 2012 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtaine