178 Advances in Anatomy Embryology and Cell Biology
Editors F. F. Beck, Melbourne · B. Christ, Freiburg F. Clascá, Madrid · D. E. Haines, Jackson H.-W. Korf, Frankfurt · W. Kummer, Giessen E. Marani, Leiden · R. Putz, München Y. Sano, Kyoto · T. H. Schiebler, Würzburg K. Zilles, Düsseldorf
S. Milz · M. Benjamin · R. Putz
Molecular Parameters Indicating Adaptation to Mechanical Stress in Fibrous Connective Tissue With 15 Figures and 13 Tables
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PD Dr. med. Stefan Milz AO Research Institute Clavadelerstrasse 7270 Davos Switzerland e-mail:
[email protected] Professor Michael Benjamin School of Biosciences Cardiff University Museum Avenue, PO Box 911 Cardiff CF10 3US United Kingdom e-mail:
[email protected] Professor Dr. med. Dr. hc. Reinhard Putz Anatomische Anstalt Pettenkoferstr. 11 80336 München Germany e-mail:
[email protected]
Library of Congress Catalog Number 2004117783 ISSN 0301-5556 ISBN-10 3-540-24474-3 Springer Berlin Heidelberg New York ISBN-13 978-3-540-24474-5 Springer Berlin Heidelberg New York
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List of Contents
1 1.1 1.2
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1 1
1.3
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . General Remarks . . . . . . . . . . . . . . . . . . . . . . . . Adaptation of Connective and Supportive Tissues to Their Respective Functions . . . . . . . . . . . . . . . Parameters of Functional Adaptation . . . . . . . . .
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2 4
2 2.1 2.2 2.3
Aim of the Study . . . . . . . . . . Fundamental Consideratio