Antibiotics And Antiseptics In Periodontal Therapy

Antibiotics and Antiseptics in Periodontal Therapy Alexandrina L. Dumitrescu Antibiotics and Antiseptics in Periodontal Therapy Author Dr. Alexandrina L. Dumitrescu University of Tromsø Institute of Clinical Dentistry Department of Periodontology 9037 Tromsø Norway [email protected] ISBN 978-3-642-13210-0 e-ISBN 978-3-642-13211-7 DOI 10.1007/978-3-642-13211-7 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2010937957 © Springer-Verlag Berlin Heidelberg 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is ­concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant ­protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: eStudio Calamar, Figueres/Berlin Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Preface Periodontitis is defined as an inflammatory disease of the periodontium characterized by inflammation of the gingival and adjacent attachment apparatus, illustrated by loss of clinical attachment due to destruction of the periodontal ligament and loss of the adjacent supporting bone. Periodontitis represents the major cause of tooth loss in adults leading to long-term disability and increased treatment needs. It is well established that the various periodontal diseases are caused by bacterial infection. Dental plaque was defined as “matrix-enclosed bacterial populations adherent to each other and/or to surfaces or interfaces”. Dental plaque is a microbial biofilm, a diverse microbial community found on the tooth surface embedded in a matrix of polymers of bacterial and salivary origin. This complex biofilm may offer some protection from the host’s immunologic mechanisms as well as chemotherapeutic agents used for treat