Cover photo credit: Hewison, M. Vitamin D and innate and adaptive immunity. Vitamins and Hormones (2011) 86, pp. 23-62. Academic Press is an imprint of Elsevier 32 Jamestown Road, London, NW1 7BY, UK Radarweg 29, PO Box 211, 1000 AE Amsterdam, The Netherlands Linacre House, Jordan Hill, Oxford OX2 8DP, UK 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA 525 B Street, Suite 1900, San Diego, CA 92101-4495, USA First edition 2011 Copyright # 2011 Elsevier Inc. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email:
[email protected] Alternatively you can submit your request online by visiting the Elsevier web site at http://elsevier.com/locate/permissions, and selecting Obtaining permission to use Elsevier material Notice No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made ISBN: 978-0-12-386960-9 ISSN: 0083-6729 For information on all Academic Press publications visit our website at elsevierdirect.com Printed and bound in USA 11 12 13 14 10 9 8 7 6 5 4 3 2 1 Former Editors ROBERT S. HARRIS KENNETH V. THIMANN Newton, Massachusetts University of California Santa Cruz, California JOHN A. LORRAINE University of Edinburgh Edinburgh, Scotland PAUL L. MUNSON University of North Carolina Chapel Hill, North Carolina JOHN GLOVER University of Liverpool Liverpool, England GERALD D. AURBACH Metabolic Diseases Branch National Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health Bethesda, Maryland IRA G. WOOL University of Chicago Chicago, Illinois EGON DICZFALUSY Karolinska Sjukhuset Stockholm, Sweden ROBERT OLSEN School of Medicine State University of New York at Stony Brook Stony Brook, New York DONALD B. MCCORMICK Department of Biochemistry Emory University School of Medicine, Atlanta, Georgia Copyright Pages iv-v Contributors Pages xiii-xvi Preface Pages xvii-xviii Gerald Litwack Chapter one - Vitamin D Regulation of Immune Function Pages 1-21 Daniel D. Bikle Chapter two - Vitamin D and Innate and Adaptive Immunity Pages 23-62 Martin Hewison Chapter three - Dendritic Cells Modified by Vitamin D: Future Immunotherapy for Autoimmune Diseases Pages 63-82 Ayako Wakatsuki Pedersen, Mogens Helweg Claesson, Mai-Britt Zocca Chapter four - Retinoic Acid, Immunity, and Inflammation Pages 83-101 Chang H. Kim Chapter five - Vitamin A and Retinoic Acid in the Regulation of B-Cell Development and Antibody Production Pages 103-126 A. Catharine Ross, Qiuyan Chen, Yifan Ma Chapter Six - Retinoic Acid Production by Intestinal Dendritic Cells Pages 127-152 Makoto Iwata, Aya Yokota Chapter seven - Immune Regulator Vitamin A and T Cell Death Pages 153-178 Nikolai Engedal Chapter eight - Vitamin E and Immunity Pages 179-215 Didem Pekmezci Chapter Nine - Vitamin D Effects on Lung Immunity and Respiratory Diseases Pages 217-237 Sif Hansdottir, Martha M. Monick Chapter Ten - Maternal Vitamin D During Pregnancy and Its Relation to Immune-Mediated Diseases in the Offspring Pages 239-260 M.