Understanding Neuropsychiatric Disorders: Insights From Neuroimaging

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E-Book Overview

An informative and comprehensive review from the leading researchers in the field, this book provides a complete one-stop guide to neuroimaging techniques and their application to a wide range of neuropsychiatric disorders. For each disorder or group of disorders, separate chapters review the most up-to-date findings from structural imaging, functional imaging and/or molecular imaging. Each section ends with an overview from a internationally-renowned luminary in the field, addressing the question of 'What do we know and where are we going?' Richly illustrated throughout, each chapter includes a 'summary box', providing readers with explicit take-home messages. This is an essential resource for clinicians, researchers and trainees who want to learn how neuroimaging tools lead to new discoveries about brain and behaviour associations in neuropsychiatric disorders.

E-Book Content

This page intentionally left blank Understanding Neuropsychiatric Disorders: Insights from Neuroimaging Understanding Neuropsychiatric Disorders: Insights from Neuroimaging Edited by Martha E. Shenton Bruce I. Turetsky CAMBRIDGE UNIVERSITY PRESS Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo, Delhi, Dubai, Tokyo, Mexico City Cambridge University Press The Edinburgh Building, Cambridge CB2 8RU, UK Published in the United States of America by Cambridge University Press, New York www.cambridge.org Information on this title: www.cambridge.org/9780521899420 # Cambridge University Press 2011 This publication is in copyright. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published 2011 Printed in the United Kingdom at the University Press, Cambridge A catalog record for this publication is available from the British Library Library of Congress Cataloging in Publication Data Understanding neuropsychiatric disorders: insights from neuroimaging / edited by Martha E. Shenton, Bruce I. Turetsky. p. cm. Includes bibliographical references and index. ISBN 978 0 521 89942 0 (Hardback) 1. Neurobehavioral disorders–Imaging. I. Shenton, Martha Elizabeth. II. Turetsky, Bruce I., 1950– [DNLM: 1. Mental Disorders–diagnosis. 2. Diagnostic Imaging– methods. WM 141 U55 2010] RC473.B7U53 2010 616.8–dc22 2010018055 ISBN 978 0 521 89942 0 Hardback Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate. Every effort has been made in preparing this book to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors and publishers therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this book. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use. Contents List of contributors Preface xiii vii Section I – Schizophrenia 1 Structural imaging of schizophrenia Thomas J. Whitford, Marek Kubicki and Martha E. Shenton 2 Functional imaging of schizophrenia Godfrey D. Pearlson 3 Spectroscopic