E-Book Content
PHAGOCYTOSIS" THE HOST
Volume 5
9 1999
ADVANCES IN CELL AND MOLECULAR BIOLOGY OF MEMBRANESAND ORGANELLES
DEDICATION
This volume is dedicated to the memory of Zanvil A. Cohn, mentor and friend.
PHAGOCYTOSIS: THE HOST Volume 5
91999
ADVANCES IN CELL AND MOLECULAR BIOLOGY OF MEMBRANES AND ORGANELLES
Series Editor:
ALAN M. TARTAKOFF
Institute of Pathology Case Western Reserve University
Volume Editor: SIAMON GORDON Sir William Dunn School of Pathology University of Oxford
JAI PRESS INC.
Stamford, Connecticut
Copyright 91999 JAI PRESSINC. 1(30 Prospect Street Stamford, Connecticut 06901 All rights reserved. No part of this publication may be reproduced, stored on a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, filming, recording, or otherwise, without prior permission in writing from the publisher. ISBN: 1-55938-999-0 Transferred to digital printing 2006
CONTENTS LIST OF CONTRIBUTORS
ix
INTRODUCTION TO THE SERIES
XV
PREFACE
Siamon Gordon
~176
XVII
SECTION I.
CONTEXT
THE EARLY HISTORY OF PHAGOCYTOSIS
Thomas P. Stossel
DROSOPHILA HEMOCYTES, PHAGOCYTOSIS, AND CROQUEMORT, A MACROPHAGE RECEPTOR Nathalie C. Franc
19
PHAGOCYTOSIS BY NONPROFESSIONAL PHAGOCYTES
Debora Williams-Herman and Zena Werb SECTION II.
47
RECEPTORS
SCAVENGER RECEPTORSAND PHAGOCYTOSIS OF BACTERIA AND APOPTOTIC CELLS
Nick Platt, Richard Haworth, Rosangela P. da Silva, and Siamon Gordon
71
MANNOSE RECEPTORAND PHAGOCYTOSIS
lain P. Fraser and R. Alan B. Ezekowitz
87
INTEGRIN RECEPTORSOF PHAGOCYTES Scott D. Blystone and Eric J. Brown
103
FC RECEPTOR-MEDIATED PHAGOCYTOSIS Steven Greenberg
149
vi
CONTENTS SECTION i11. SIGNALING
HETEROGENEITY IN MACROPHAGE PHAGOCYTOSIS Alan Aderem and David M. Underhill SIGNALING THROUGH RHO GTPASESIN PHAGOCYTES
Arie E. Abo
195
215
REGULATORY ROLESOF PHOSPHATIDYLINOSITOL (4,5) BISPHOSPHATE IN CELLSIGNALING, MEMBRANE TRAFFIC, AND THE CYTOSKELETON
Shamshad Cockcroft
233
SECTION IV. THE PATHWAY PATHWAYS THROUGH THE MACROPHAGE VACUOLAR COMPARTMENT
Joel A. Swanson
267
SEQUENTIAL MATURATION OF PHAGOSOMES PROVIDES UNIQUE TARGETS FOR PATHOGENS
Carmen Alvarez-Dominguez, Luis Mayorga, and Philip D. Stahl
PHAGOSOMAL ACIDIFICATION: MECHANISMS AND FUNCTIONAL SIGNIFICANCE
David J. Hackam, Off D. Rotstein, and Sergio Grinstein
285
299
THE PHAGOCYTEACTIN CYTOSKELETON
Hui-Qiao Sun, Keng-Mean Lin, Masaya Yamamoto, and Helen L. Yin 321 SECTION V.
RESPONSES
NRAMPI: A NOVEL MACROPHAGE PROTEIN WITH A KEY FUNCTION IN RESISTANCETO INTRACELLULAR PATHOGENS
Samantha Gruenheid, Emil Skamene, and Philippe Gros
345
UPTAKE AND PRESENTATION OF PHAGOCYTOSED ANTIGENS BY DENDRITIC CELLS
Matthew L. Albert, Shannon Turley, Wendy Garrett, Ira Mellman, Kayo Inaba, Nina Bhardwaj, and Ralph M. Steinman
363
Contents
vii
PROCESSING AND PRESENTATION OF PHAGOCY'IOSED ANTIGENS TO THE IMMUNE SYSTEM
Jean Pieters
ANTIMICROBIAL MECHANISMS OF MACROPHAGES Michael U. Shiloh and Carl F. Nathan COMPONENTS AND ORGANIZATION OF THE NADPH OXIDASE OF PHAGOCYTIC CELLS: ITS ROLE IN MICROBIAL KILLING AND IN THE MOLECULAR PATHOLOGY OF CHRONIC GRANULOMATOUS DISEASE Anthony W. Segal, Frans Wientjes, R.W. Stockley, and
Lodewijk V. Dekker
379
407
441
OXYGEN-INDEPENDENT ANTIMICR