Continuous-flow Chemistry In The Research Laboratory: Modern Organic Chemistry In Dedicated Reactors At The Dawn Of The 21st Century

Toma Glasnov ContinuousFlow Chemistry in the Research Laboratory Modern Organic Chemistry in Dedicated Reactors at the Dawn of the 21st Century Continuous-Flow Chemistry in the Research Laboratory ThiS is a FM Blank Page Toma Glasnov Continuous-Flow Chemistry in the Research Laboratory Modern Organic Chemistry in Dedicated Reactors at the Dawn of the 21st Century Toma Glasnov Institute of Chemistry University of Graz Graz Austria ISBN 978-3-319-32194-3 ISBN 978-3-319-32196-7 DOI 10.1007/978-3-319-32196-7 (eBook) Library of Congress Control Number: 2016940841 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland Preface As a result of new environment regulations, safety concerns, and the economical situation after the last crisis in 2008, there is a strong need of new innovative, environmentally friendly synthetic routes and enabling technologies to meet the new requirements. In the last few years, we have witnessed a steady growth in the field of continuous flow synthesis. The rising interest in this technology is in a direct relation with the recognition that this technique actually provides various advantages, especially in dealing with potentially hazardous chemistries, handling thermal runaways, or efficient mixing requirements. Despite the industrial background, continuous flow processing has slowly breached the barrier to academia and is now often considered as the logical choice for scaling up laboratory syntheses. However, as with every new technology, the obstacle of missing information and education on the basic principles, common problems, already existing protocols, and applications prevents its implementation in the daily research. Thus, the aim of this book is to give the reader a structured overview of known synthetic procedures involving the use of dedicated continuous flow instrumentation publ