Experimental Organic Chemistry: A Miniscale And Microscale Approach
E-Book Overview
Providing even more emphasis on inquiry-based learning, a new green experiment, and more than a dozen new discovery experiments, this Fifth Edition of Gilbert and Martin's proven EXPERIMENTAL ORGANIC CHEMISTRY contains procedures for both miniscale (also known as small scale) and microscale users. The manual first provides an early focus on equipment, record keeping, and safety in the laboratory, then walks students step by step through the laboratory techniques they need to perform the book's experiments with confidence. Chapters show students how to use the book's techniques to synthesize compounds and analyze their properties, complete multi-step syntheses of organic compounds, and solve structures of unknown compounds. A bioorganic experiment in Chapter 24 reflects the increasing emphasis on bioorganic chemistry in the course and gives students an opportunity to accomplish a mechanistically interesting and synthetically important coupling of two a-amino acids to produce a dipeptide.
E-Book Information
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Series: Brooks Cole Laboratory Series for Organic Chemistry
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Year: 2,010
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Edition: 5
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Pages: 966
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Pages In File: 966
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Language: English
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Topic: 300
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Issue: 2011 12 30
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Identifier: 1439049149,9781439049143
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Paginated: 1
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Org File Size: 55,301,756
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Extension: pdf
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Tags:
Химия и химическая промышленность
Органическая химия
Синтетические и экспериментальные методы ОХ
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Toc: Front Cover......Page 1 Title Page......Page 7 Copyright......Page 8 Table of Contents......Page 10 1.1 Introduction......Page 29 1.2 Preparing For The Laboratory......Page 30 1.3 Working In The Laboratory......Page 31 1.5 General Protocol For The Laboratory Notebook......Page 32 1.6 Types Of Organic Experiments And Notebook Formats......Page 33 1.7 Sample Calculations For Notebook Records......Page 42 1.8 Safe Laboratory Practice: Overview......Page 44 1.9 Safety: General Discussion......Page 45 1.10 Safety: Material Safety Data Sheets......Page 47 1.11 Safety: Disposal Of Chemicals......Page 49 Historical Highlight: The Importance of Record Keeping......Page 52 2.1 Glassware: Precautions And Cleaning......Page 55 2.2 Standard-Taper Glassware For Miniscale Procedures......Page 56 2.3 Standard-Taper Glassware For Microscale Procedures......Page 57 2.4 Assembling Apparatus......Page 59 2.5 Measuring And Transferring Liquids......Page 60 2.6 Weighing Methods......Page 65 2.7 Melting-Point Methods And Apparatus......Page 66 2.8 Boiling-Point Methods And Apparatus......Page 69 2.9 Heating Methods......Page 71 2.10 Cooling Techniques......Page 79 2.11 Stirring Methods......Page 80 2.12 Centrifugation......Page 82 2.13 Simple Distillation......Page 83 2.14 Fractional Distillation......Page 86 2.15 Vacuum Distillation......Page 88 2.16 Steam Distillation......Page 92