Volume 71
Epigenetics and Cancer, Part B
Advances in Genetics, Volume 71
Serial Editors
Theodore Friedmann University of California at San Diego, School of Medicine, USA
Jay C. Dunlap Dartmouth Medical School, Hanover, NH, USA
Stephen F. Goodwin University of Oxford, Oxford, UK
Volume 71
Epigenetics and Cancer, Part B Edited by
Zdenko Herceg Epigenetics Group International Agency for Research on Cancer (IARC) Lyon, France
Toshikazu Ushijima Carcinogenesis Division National Cancer Centre Research Institute Tokyo, Japan
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Contents Contributors Preface xi
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SECTION I EPIGENETIC CHANGES INDUCED BY ENVIRONMENTAL AND DIETARY/ LIFESTYLE FACTORS 1 1 Induction of Epigenetic Alterations by Dietary and Other Environmental Factors 3
John C. Mathers, Gordon Strathdee, and Caroline L. Relton I. Introduction 4 II. Induction of Epigenetic Alterations by Dietary and Other Environmental Factors 9 III. Conclusions 27 References 30
2 Induction of Epigenetic Alterations by Chronic Inflammation and Its Significance on Carcinogenesis 41 Tohru Niwa and Toshikazu Ushijima
I. Introduction 42 II. Traditional Views on How Inflammation Leads to Cancers 43 III. Epigenetic Alteration Induced by Inflammation and Its Significance on Carcinogenesis 44 IV. Mechanisms for Induct