Somitogenesis

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MIGUEL MAROTO is a MRC Career Development Fellow and Lecturer at the University of Dundee, UK. He received his PhD in Biochemistry and Molecular Biology from the Department of Biochemistry of the Universidad Autonoma of Madrid, Spain. His research interests include investigating the biochemical basis of different signalling mechanisms implicated in the acquisition of specific cell fates during vertebrate development. In recent years he has been involved in the analysis of the mechanism of the molecular clock in the control of the process of somitogenesis.

NEIL V. WHITTOCK gained his PhD in Human Molecular Genetics whilst working at Guys’ and St Thomas’ Hospitals in London, UK. His research focussed on developing diagnostic genetic tests for Duchenne muscular dystrophy before moving on to identifying genes involved in bullous skin disorders. He then continued his research as a postdoctoral fellow at the University of Dundee before arriving at the University of Exeter where he spent three years working alongside Dr Peter Turnpenny. The work at Exeter focussed on the identification of genes involved in human genetic disorders that affected the development of the spine and ribs, specifically the spondylocostal dysostoses. He now works as an Ambulance Technician in Devon, UK. and runs his own antique clock restoration business.


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Somitogenesis ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University ofNew York at Buffalo IRUN R. COHEN, The Weizmann Institute ofScience ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research JOHN D. LAMBRIS, University ofPennsylvania RODOLFO PAOLETTI, University ofMilan Recent Volumes in this Series Volume 630 INNOVATIVE ENDOCRINOLOGY OF CANCER Edited by Lev M. Berstein and Richard J. Santen Volume 631 BACTERIAL SIGNAL TRANSDUCTION Edited by Ryutaro Utsumi Volume 632 CURRENT TOPICS IN COMPLEMENT II Edited by John. D. Lambris Volume 633 CROSSROADS BETWEEN INNATE AND ADAPTIVE IMMUNITY II Edited by Stephen P. Schoenberger, Peter D. Katsikis, and Bali Pulendran Volume 634 HOT TOPICS IN INFECTION AND IMMUNITY IN CIDLDREN V Edited by Adam Finn, Nigel Curtis, and Andrew J. Pollard Volume 635 GI MICROBIOTAAND REGULATION OF THE IMMUNE SYSTEM Edited by Gary B. Huffnagle and Mairi Noverr Volume 636 MOLECULAR MECHANISMS IN SPERMATOGENESIS Edited by C. Yan Cheng Volume 637 MOLECULAR MECHANISMS IN XERODERMA PIGMENTOSUM Edited by Shamin Ahmad and Fumio Hanaoka Volume 638 SOMITOGENESIS Edited by Miguel Maroto and Neil V. Whittock A ContinuationOrder Plan is availablefor this series.A continuation order will bring delivery of each new volume immediately upon publication. Volwnesare billed only upon actual shipment. For further information please contact the publisher. Somitogenesis Edited by Miguel Maroto, PhD University ofDundee, Dundee, Scotland Neil V. Whittock, PhD University ofExeter, Devon, England Springer Science+Business Media, LLC Landes Bioscience Springer Science+Business Media, LLC Landes Bioscience Copyright ©2008 Landes Bioscience and Springer Science-Business Media , LLC All rights reserved. No part ofthis book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system; for exclusive use by the Purchaser of the work. Printed in the USA Springer Science-Business Media, LLC, 233 Spring Street, New York, New York 10013, USA http ://www.springer.com Please address all inquiries to the publishers: Landes Bioscience, 1002 West Avenue, Austin, Texas 7870 I, USA Phone : 512/6375060; FAX: 512/6