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CH.DDE.H.Pylori.aFM_F 3/6/08 9:11 AM Page 1 HELICOBACTER PYLORI CH.DDE.H.Pylori.aFM_F 3/6/08 9:11 AM Page 2 Anthrax Malaria Antibiotic-resistant Bacteria Meningitis Avian Flu Botulism Campylobacteriosis Cervical Cancer Cholera Ebola Encephalitis Mononucleosis Pelvic Inflammatory Disease Plague Polio Prostate Cancer Rabies Escherichia coli Infections Salmonella Gonorrhea Smallpox Hantavirus Pulmonary Syndrome Streptococcus (Group A) Helicobacter pylori SARS Hepatitis Staphylococcus aureus Infections Herpes Syphilis HIV/AIDS Toxic Shock Syndrome Infectious Fungi Influenza Legionnaires’ Disease Leprosy Lyme Disease Lung Cancer Mad Cow Disease (Bovine Spongiform Encephalopathy) Tuberculosis Tularemia Typhoid Fever West Nile Virus CH.DDE.H.Pylori.aFM_F 3/6/08 9:11 AM Page 3 HELICOBACTER PYLORI Shawna L. Fleming, Ph.D. FOUNDING EDITOR The Late I. Edward Alcamo Distinguished Teaching Professor of Microbiology, SUNY Farmingdale FOREWORD BY David Heymann World Health Organization CH.DDE.H.Pylori.aFM_F 3/6/08 9:11 AM Page 4 Helicobacter pylori Copyright © 2007 by Infobase Publishing All rights reserved. No part of this book may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage or retrieval systems, without permission in writing from the publisher. For information contact: Chelsea House An imprint of Infobase Publishing 132 West 31st Street New York NY 10001 Library of Congress Cataloging-in-Publication Data Fleming, Shawna L. Helicobacter pylori / Shawna L. Fleming ; foreword by David Heyman. p. cm.—(Deadly diseases and epidemics) Includes bibliographical references and index. ISBN 0-7910-8681-X (hc : alk. paper) 1. Helicobacter pylori infections—Juvenile literature. 2. Helicobacter pylori— Juvenile literature. I. Title. II. Series. RC 840.H38F54 2006 616.3’3014—dc22 2006015153 Chelsea House books are available at special discounts when purchased in bulk quantities for businesses, associations, institutions, or sales promotions. Please call our Special Sales Department in New York at (212) 967-8800 or (800) 322-8755. You can find Chelsea House on the World Wide Web at http://www.chelseahouse.com Series design by Terry Mallon Cover design by Takeshi Takahashi Printed in the United States of America Bang EJB 10 9 8 7 6 5 4 3 2 1 This book is printed on acid-free paper. All links and Web addresses were checked and verified to be correct at the time of publication. Because of the dynamic nature of the Web, some addresses and links may have changed since publication and may no longer be valid. CH.DDE.H.Pylori.aFM_F 3/6/08 9:11 AM Page 5 Table of Contents Foreword David Heymann, World Health Organization 6 1. The Discovery of Helicobacter pylori 8 2. The Anatomy and Physiology of Digestion: What Happens to the Food that You Eat? 24 H. pylori: Its Biology and Its Survival in the Stomach 43 4. Who Is Infected with H. pylori ? 54 5. H. pylori and Ulcers 65 6. H. pylori and the Immune System 72 7. The Role of H. pylori in Cancer and Autoimmune Diseases 84 Diagnosis and Treatment of H. pylori 96 3. 8. Glossary 111 Additional Resources 120 Bibliography 123 Index 135<