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Table of Contents 15 April 2005 Volume 308 Number 5720 Ecological Impacts of Timber Trade Synthetic Route to Improved Antibiotics Genetic Clue to Macular Degeneration Human Impacts on River Flow Flies and Mice Repair Alike SPECIAL FEATURE EDITORIAL FEATURE: Keys to Independence in the U.K. and Ireland Anne Forde and Elisabeth Pain 427-428. EDITORIAL FEATURE: Views From the Trenches Anne Forde and Elisabeth Pain 428-430. RESEARCH This Week in Science Open Access to Sea Levels * Damming Analysis * Tracking a Solid-Liquid Transition * Limits on Spin Entanglement? * Tetracyclines from Scratch * Last Gasps * Blinded by a Complement * Let's Get Together * Keeping Up Defenses * Malaria Membrane Protein Structure * The Making of a Simple Timepiece * Keep Your Eyes on the Ball 321 Editors' Choice: Highlights of the recent literature EARTH SCIENCE: Forecast: Rain, Less and More * CHEMISTRY: Flexible Dendrimer Synthesis * PLANT BIOLOGY: Closing the Wound * ECOLOGY/EVOLUTION: Too Much of a Good Thing * CHEMISTRY: Stitching Siloxanes * PSYCHOLOGY: Genes and Environment * CELL BIOLOGY: Front and Back 326 Review Unveiling the Mechanisms of Cell-Cell Fusion Elizabeth H. Chen and Eric N. Olson 369-373. Brevia A Pair of Shelled Eggs Inside A Female Dinosaur Tamaki Sato, Yen-nien Cheng, Xiao-chun Wu, Darla K. Zelenitsky, and Yu-fu Hsiao 375. Research Article Impact of Humans on the Flux of Terrestrial Sediment to the Global Coastal Ocean James P. M. Syvitski, Charles J. Vörösmarty, Albert J. Kettner, and Pamela Green 376-380. An Epidermal Barrier Wound Repair Pathway in Drosophila Is Mediated by grainy head Kimberly A. Mace, Joseph C. Pearson, and William McGinnis 381-385. I Complement Factor H Polymorphism in Age-Related Macular Degeneration Robert J. Klein, Caroline Zeiss, Emily Y. Chew, Jen-Yue Tsai, Richard S. Sackler, Chad Haynes, Alice K. Henning, John Paul SanGiovanni, Shri