E-Book Overview
This book represents the first of the ALZA CONFERENCE SERIES which will deal with a wide variety of topics of biomedical interest. These Conferences are planned to cover a range of subjects from the molecular level, such as drug receptor and drug membrane interactions, to the organ and organismal levels and the dynamics of drug therapy. This year's topic is "PROSTAGLANDINS." It is rapidly becoming clear that prosta glandins are of great interest and potential utility in therapeutics. An understanding of the role of prostaglandins in the regulation of cell processes should provide insight into the understanding of a variety of difficult and intransigent fields such as cancer, allergy, and transplant rejection. We hope that this Conference may focus attention on novel approaches to these areas. We wish to thank our distinguished Chairmen and guests for their attendance. The papers and dis cussions were prepared by Yvonne Hendrickson, using an ATS/360 Text-Editing System; we acknowledge with gratitude her skill, patience, and hard work. P.W.R. B.B.P.
E-Book Information
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Series: Alza Conference Series 195B
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Year: 1,972
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Edition: 1
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Pages: 526
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Pages In File: 526
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Language: English
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Identifier: 978-1-4684-2846-9,978-1-4684-2844-5
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Doi: 10.1007/978-1-4684-2844-5
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Cleaned: 1
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Orientation: 1
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Paginated: 1
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Org File Size: 39,842,019
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Extension: pdf
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Tags: Biochemistry, general
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Toc: Front Matter....Pages i-xiIntroductory Remarks to the First Session....Pages 1-4Use of Prostaglandins in the Preparation of Blood Components....Pages 5-25Some Effects of Vasoactive Hormones on the Mammalian Red Blood Cell....Pages 27-60Use of PGE(1) in Preparation and Storage of Platelet Concentrates....Pages 61-76Prostaglandin E(1) and E(2): Qualitative Difference in Platelet Aggregation....Pages 77-92The Effect of Prostaglandins, Epinephrine and Aspirin on Cyclic AMP Phospho Diesterase Activity of Human Blood Platelets and Their Aggregation....Pages 93-110Leukocyte Cyclic AMP: Pharmacological Regulation and Possible Physiological Implications....Pages 111-149Effect of Prostaglandins upon Enzyme Release from Lysosomes and Experimental Arthritis....Pages 151-172The Role of Prostaglandins in the Immune Response....Pages 173-194The Role of Prostaglandins in the Regulation of Growth and Morphology of Transformed Fibroblasts....Pages 195-205Prostaglandin Release by Human Cells In Vitro ....Pages 207-226Release and Actions of Prostaglandins in Inflammation and Fever: Inhibition by Anti-Inflammatory and Antipyretic Drugs....Pages 227-268Formation of Prostaglandins in the Skin Following a Burn Injury....Pages 269-291Prostaglandin Inhibition of Immediate and Delayed Hypersensitivity in Vitro ....Pages 293-308The Role of Prostaglandins in Microcirculatory Regulation and Inflammation....Pages 309-327Pro-Inflammatory Effects of Certain Pros