The Mouse in Biomedical Research, 2nd Edition Volume IV Immunology This page intentionally left blank THE MOUSE IN BIOMEDICAL RESEARCH, 2ND EDITION Volume IV Immunology EDITED BY James G. Fox Muriel T. Davisson Fred W. Quimby Division of Comparative Medicine, MIT Cambridge, MA The Jackson Laboratory Bar Harbor, ME Laboratory Animal Research Center The Rockefeller University New York, NY Stephen W. Barthold Christian E. Newcomer Abigail L. Smith Center for Comparative Medicine Schools of Medicine and Veterinary Medicine University of California Davis, CA Research Animal Resources and Department of Molecular and Comparative Pathobiology Johns Hopkins University Baltimore, MD School of Veterinary Medicine University of Pennsylvania Philadelphia, PA AMSTERDAM • BOSTON • HEIDELBERG • LONDON • NEW YORK • OXFORD PARIS • SAN DIEGO • SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO Academic Press is an imprint of Elsevier Academic Press is an imprint of Elsevier 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA 525 B Street, Suite 1900, San Diego, California 92101-4495, USA 84 Theobald’s Road, London WC1X 8RR, UK This book is printed on acid-free paper. Copyright © 2007, Elsevier, Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone: (+44) 1865 843830, fax: (+44) 1865 853333, E-mail:
[email protected] You may also complete your request on-line via the Elsevier homepage (http://elsevier.com), by selecting “Support & Contact” then “Copyright and Permission” and then “Obtaining Permissions.” Library of Congress Cataloging-in-Publication Data Application Submitted British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library. ISBN 13: 978-0-12-369458-4 (v. 4) ISBN 10: 0-12-369458-2 (v.4) ISBN-Set: 0-12-369454-X For information on all Academic Press publications visit our Web site at www.books.elsevier.com Printed in the United States of America 07 08 09 10 9 8 7 6 5 4 3 2 1 Table of Contents Volume I History, Wild Mice, and Genetics List of Reviewers List of Contributors Foreword Preface 1. Building a Better Mouse: One Hundred Years of Genetics and Biology x xi xiii xv 10. 1 Herbert C. Morse III Mouse Embryology: Research Techniques and a Comparison