E-Book Overview
Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is an invaluable source for drug discovery and development scientists in the biopharmaceutical industry who frequently navigate the maze of protein and peptide pharmacokinetics, pharmacodynamics, and metabolism. Key features include:
E-Book Content
Proteins and Peptides DRUGS AND THE PHARMACEUTICAL SCIENCES A Series of Textbooks and Monographs Executive Editor James Swarbrick PharmaceuTech, Inc. Pinehurst, North Carolina Advisory Board Larry L. Augsburger University of Maryland Baltimore, Maryland Jennifer B. Dressman University of Frankfurt Institute of Pharmaceutical Technology Frankfurt, Germany Anthony J. Hickey University of North Carolina School of Pharmacy Chapel Hill, North Carolina Ajaz Hussain Sandoz Princeton, New Jersey Joseph W. Polli GlaxoSmithKline Research Triangle Park North Carolina Stephen G. Schulman Harry G. Brittain Center for Pharmaceutical Physics Milford, New Jersey Robert Gurny Universite de Geneve Geneve, Switzerland Jeffrey A. Hughes University of Florida College of Pharmacy Gainesville, Florida Vincent H. L. Lee US FDA Center for Drug Evaluation and Research Los Angeles, California Kinam Park Purdue University West Lafayette, Indiana Jerome P. Skelly Alexandria, Virginia University of Florida Gainesville, Florida Elizabeth M. Topp Yuichi Sugiyama University of Kansas Lawrence, Kansas University of Tokyo, Tokyo, Japan Geoffrey T. Tucker University of Sheffield Royal Hallamshire Hospital Sheffield, United Kingdom Peter York University of Bradford School of Pharmacy Bradford, United Kingdom For information on volumes 1–152 in the Drugs and Pharmaceutical Science Series, please visit www.informahealthcare.com 153. Pharmaceutical Stress Testing: Predicting Drug Degradation, edited by Steven W. Baertschi 154. Handbook of Pharmaceutical Granulation Technology: Second Edition, edited by Dilip M. Parikh 155. Percutaneous Absorption: Drugs–Cosmetics–Mechanisms–Methodology, Fourth Edition, edited by Robert L. Bronaugh and Howard I. Maibach 156. Pharmacogenomics: Second Edition, edited by Werner Kalow, Urs A. Meyer and Rachel F. Tyndale 157. Pharmaceutical Process Scale-Up, Second Edition, edited by Michael Levin 158. Microencapsulation: Methods and Industrial Applications, Second Edition, edited by Simon Benita 159. Nanoparticle Technology for Drug Delivery, edited by Ram B. Gupta and Uday B. Kompella 160. Spectroscopy of Pharmaceutical Solids, edited by Harry G. Brittain 161. Dose Optimization in Drug Development, edited by Rajesh Krishna 162. Herbal Supplements-Drug Interactions: Scientific and Regulatory Perspectives, edited by Y. W. Francis Lam, Shiew-Mei Huang, and Stephen D. Hall 163. Pharmaceutical Photostability and Stabilization Technology, edited by Joseph T. Piechocki and Karl Thoma 164. Environmental Monitoring for Cleanrooms and Controlled Environments, edited by Anne Marie Dixon 165. Pharmaceutical Product Development: In Vitro-In Vivo Correlation, edited by Dakshina Murthy Chilukuri, Gangadhar Sunkara, and David Young 166. Nanoparticulate Drug Delivery Systems, edited by Deepak Thassu, Michel Deleers, and Yashwant Pathak 167. Endotoxins: Pyrogens, LAL Testing and Depyrogenation, Third Edition, edited by Kevin L. Williams 168. Good Laboratory Practice Regulations, Fourth Edition, edited by Anne Sandy Weinberg 169. Good Manufacturing Practices for Pharmaceuticals, Sixth Edition,