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Esophageal cancer is a relatively uncommon but highly lethal malignancy. The incidence of adenocarcinoma is rapidly increasing and improved survival will depend on prevention, earlier diagnosis, improved staging and appropriate treatment. The multidisciplinary team approach toward patient care is critical in determining the management of patients with esophageal cancer. This volume provides a detailed review of new endoscopic methods of diagnosis, staging using both conventional and functional imaging and assessment of surgical and medical methods of therapy, providing all members of the team with a detailed overview of the diagnosis and management of this malignancy.
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This page intentionally left blank Carcinoma of the Esophagus Contemporary Issues in Cancer Imaging A Multidisciplinary Approach Series Editors Rodney H. Reznek Cancer Imaging, St. Bartholomew’s Hospital, London Janet E. Husband Diagnostic Radiology, Royal Marsden Hospital, Surrey Current titles in the series Cancer of the Ovary Lung Cancer Colorectal Cancer Carcinoma of the Kidney Forthcoming titles in the series Carcinoma of the Bladder Prostate Cancer Squamous Cell Cancer of the Neck Pancreatic Cancer Interventional Radiological Treatment of Liver Tumours Carcinoma of the Esophagus Edited by Sheila C. Rankin Series Editors Rodney H. Reznek Janet E. Husband CAMBRIDGE UNIVERSITY PRESS Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo Cambridge University Press The Edinburgh Building, Cambridge CB2 8RU, UK Published in the United States of America by Cambridge University Press, New York www.cambridge.org Information on this title: www.cambridge.org/9780521882859 © Cambridge University Press 2008 This publication is in copyright. Subject to statutory exception and to the provision of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published in print format 2007 ISBN-13 978-0-511-37745-7 eBook (EBL) ISBN-13 978-0-521-88285-9 hardback Cambridge University Press has no responsibility for the persistence or accuracy of urls for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate. Every effort has been made in preparing this publication to provide accurate and up-todate information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors, and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors, and publishers therefore disclaimall liability for direct or consequential damages resulting fromthe use of material contained in this publication. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use. Contents Contributors Series foreword Preface to Carcinoma of the Esophagus vii ix xi 1 Epidemiology and Clinical Presentation in Esophageal Cancer Satvinder S. Mudan and Jin-Yong Kang 1 2 Pathology of Esophageal Cancer Harriet M. R. Deere 14 3 Recent Advances in the Endoscopic Diagnosis of Esophageal Cancer Anne Marie Lennon and Ian D. Penman 28 4 Endoscopic Ultrasound in Esophageal Cancer Anne Marie Lennon and Ian D. Penman 44 5 CT in Eso