E-Book Overview
Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach.This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories. Key Features* Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system* Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function* Written in clear language that is easily understandable to readers not already familiar with fruit fly research* Includes numerous diagrams and extensive reference lists
E-Book Content
REVIEW
IN
OF
REVIEW OF
SERIES EDITORS
RONALD J. BRADLEY Department ofPsychiat?y, School ofMedicine Louisiana State University Medical Center Shreueport, Louisiana, USA
R. ADRON HARRIS Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado, USA
PETER J E NNER Biomedical Sciences Division, King's College, London, UK
EDITORIAL BOARD PHlLlPPE ASCHER ROSS J. BALDESSARINI TAMAS BARTFAI COLIN BCAKEMORE FLOYD E. BLOOM DAVID A. BROWN MATTHEW J. DURING KJELL FUXE PAUL GREENGARD SUSAN 0. IVERSEN
KINYA KURIYAMA BRUCE S. MCEWEN HERBERT Y. MELTZER NOBORU MIZUNO SALVADOR MONCADA TREVOR W. ROBBINS SOLOMON H. SNYDER STEPHEN G. WAXMAN CHIEN-PING WU RICHARD J. WYATT
EDITED BY
VIVIAN BUDNIK Department of Biology and Molecular and Cellular Biology Program University of Massachusetts Amherst, Massachusetts, USA
L.SIAN GRAMATES Department of Biology and Molecular and Cellular Biology Program University of Massachusetts Amherst, Massachusetts, USA
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Coverphoto: Neuromuscular junction of muscles 12 and 13 of a third instar Drosophila larva, immunolabeled with or-HRP. Confocal micrograph by Dr. Michael Gorczyca
This book is printed on acid-free paper.
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