V O LU M E
S E V E N
ADVANCES IN PLANAR LIPID BILAYERS AND LIPOSOMES
EDITORIAL BOARD Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor Professor
Dr. Roland Benz (Wuerzburg, Germany) Dr. Hans G.L. Coster (Sydney, Australia) Dr. Herve Duclohier (Rennes, France) Dr. Yury A. Ermakov (Moscow, Russia) Dr. Alessandra Gliozzi (Genova, Italy) Dr. Alesˇ Iglicˇ (Ljubljana, Slovenia) Dr. Bruce L. Kagan (Los Angeles, USA) Dr. Wolfgang Knoll (Mainz, Germany) Dr. Reinhard Lipowsky (Potsdam, Germany) Dr. Yoshinori Muto (Gifu, Japan) Dr. Ian R. Peterson (Coventry, UK) Dr. Alexander G. Petrov (Sofia, Bulgaria) Dr. Jean-Marie Ruysschaert (Bruxelles, Belgium) Dr. Bernhard Schuster (Vienna, Austria) Dr. Masao Sugawara (Tokyo, Japan) Dr. Yoshio Umezawa (Tokyo, Japan) Dr. Erkang Wang (Changchun, China) Dr. Philip J. White (Wellesbourne, UK) Dr. Mathias Winterhalter (Bremen, Germany) Dr. Dixon J. Woodbury (Provo, USA)
V O LU M E
S E V E N
ADVANCES IN PLANAR LIPID BILAYERS AND LIPOSOMES Editor
PROFESSOR DR. A. LEITMANNOVA LIU Department of Physiology, Michigan State University, East Lansing, Michigan, USA and Centre for Interface Sciences, Microelectronics Department, Faculty of Electrical Engineering & Information Technology, Slovak Technical University, Bratislava, Slovak Republic Founding Editor
PROFESSOR DR. H.T. TIEN Department of Physiology, Michigan State University, East Lansing, Michigan, USA
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ACADEMIC PRESS
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CONTENTS
Preface Contributors
1. Random Processes in the Appearance and Dynamics of an Electropore in a Lipid Membrane
xi xiii
1
Malgorzata Kotulska and Krystian Kubica 1. Introduction 2. Lipid Membrane—Structure and Dynamics 2.1. Lipid Conformation 2.2. Random Movements of Lipids Molecules 2.3. MC Methods in Modeling Membranes 3