E-Book Content
About this PDF file: This new digital representation of the original work has been recomposed from XML files created from the original paper book, not from the original typesetting files. Page breaks are true to the original; line lengths, word breaks, heading styles, and other typesetting-specific formatting, however, cannot be retained, and some typographic errors may have been accidentally inserted. Please use the print version of this publication as the authoritative version for attribution.
i
COLLOQUIUM ON NEUROBIOLOGY OF PAIN
NATIONAL ACADEMY OF SCIENCES WASHINGTON, D.C. 1999
About this PDF file: This new digital representation of the original work has been recomposed from XML files created from the original paper book, not from the original typesetting files. Page breaks are true to the original; line lengths, word breaks, heading styles, and other typesetting-specific formatting, however, cannot be retained, and some typographic errors may have been accidentally inserted. Please use the print version of this publication as the authoritative version for attribution.
COLLOQUIUM SERIES
ii
NATIONAL ACADEMY OF SCIENCES Colloquium Series In 1991, the National Academy of Sciences inaugurated a series of scientific colloquia, five or six of which are scheduled each year under the guidance of the NAS Council’s Committee on Scientific Programs. Each colloquium addresses a scientific topic of broad and topical interest, cutting across two or more of the traditional disciplines. Typically two days long, colloquia are international in scope and bring together leading scientists in the field. Papers from colloquia are published in the Proceedings of the National Academy of Sciences (PNAS).
About this PDF file: This new digital representation of the original work has been recomposed from XML files created from the original paper book, not from the original typesetting files. Page breaks are true to the original; line lengths, word breaks, heading styles, and other typesetting-specific formatting, however, cannot be retained, and some typographic errors may have been accidentally inserted. Please use the print version of this publication as the authoritative version for attribution.
COLLOQUIUM SERIES
National Academy of Sciences Colloquium Arnold and Mabel Beckman Center, Irvine The Neurobiology of Pain December 11–13, 1998 PROGRAM Friday, December 11, 1998 Introduction Ronald Dubner, Colloquium Organizer Session I: Channels Chair and Discussion Leader John Hunter, Department of Analgesia, Roche Bioscience Stephen G. Waxman, Department of Neurology, Yale University School of Medicine Sodium Channels and the Pathophysiology of Pain Michael Gold, Department of Oral and Craniofacial Biological Sciences, University of Maryland Dental School TTX-R INa and Inflammatory Hyperalgesia Daniel Weinreich, Department of Pharmacology and Experimental Therapeutics, University of Maryland, School of Medicine Which Potassium Channels Keep Vagal Afferent Neurons Mellow? Discussant Peter McNaughton, Department of Physiology, King’s College London Heat-Activated Ion Currents in Nociceptors–Transduction and Sensitization Session II: Receptors Chair and Discussion Leader Patrick Mantyh, Department of Preventive Sciences, School of Dentistry, University of Minnesota Amy B. MacDermott, Department of Physiology and Cellular Biophysics and Center for Neurobiology and Behavior, Columbia University AMPA and Kainate Receptor Expression by DRG Neurons in Culture Edwin W. McCleskey, Vollum Institute, Oregon Health Sciences University The Role of Sensory Modality-Selective Gene Transcription in Opioid Analgesia Michael W. Salter, Programmes in Brain and Behavior and Cell Biology, Hospital for Sick Children, and Department of Physiology, University of Toronto NMDA Receptors and Src in Synaptic Plasticity D