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Proceedings of the International Symposium on Polymer Therapeutics - Recent Progress in Clinics and Future Prospects, held July 13-14, 2001, in Nara, Japan.
The technology of polymer science has developed considerably during the past half-century, and this volume describes some of the aspects of this technology that will have a great impact in the future. Among these advances, for example, are gene delivery to specific disease sites and carrier polymers that respond to a stimulus or particular environment. Cancer targeted drug delivery is another focused area of this volume because of the important nature of EPR-effect of polymer drugs in tumor. Included are discussions of as many examples as possible of polymer drugs that have achieved, or are close to clinical use. The concept of "Polymer drugs" here is limited to primarily injectable and water-soluble agents, although also covered are some drugs in micellar form or liposomes.
This book is intended for students and researchers in the field of pharmacology who have particular interests in drug delivery, targeting, and formulation, as well as for clinicians such as oncologists who are interested in the field. People who work at regulatory agencies should also be aware such that drugs with great potential are being developed and will be beneficial to many patients, as well as to health insurance agencies because of improved cost effectiveness.
E-Book Content
POLYMER DRUGS IN THE CLINICAL STAGE ADVANTAGES AND PROSPECTS
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan
Recent Volumes in this Series Volume 510 OXYGEN TRANSPORT TO TISSUE XXIII: Oxygen Measurements in the Century: Basic Techniques and Clinical Relevance Edited by David F. Wilson, Sydney M. Evans, John Biaglow, and Anna Pastuszko Volume 511 PEDIATRIC GENDER ASSIGNMENT: A Critical Reappraisal Edited by Stephen A. Zderic, Douglas A. Canning, Michael C. Carr, and Howard McC. Snyder, III. Volume 512 LYMPHOCYTE ACTIVATION AND IMMUNE REGULATION IX: Homeostasis and Lymphocyte Traffic Edited by Sudhir Gupta, Eugene Butcher, and William Paul Volume 513 MOLECULAR AND CELLULAR BIOLOGY OF NEUROPROTECTION IN THE CNS Edited by Christian Alzheimer Volume 514 PHOTORECEPTORS AND CALCIUM Edited by Wolfgang Baehr Volume 515 NEUROPILIN: From Nervous System to Vascular and Tumor Biology Edited by Dominique Bagnard Volume 516 TRIPLE REPEAT DISEASES OF THE NERVOUS SYSTEM Edited by Lubov T. Timchenko Volume 517 DOPAMINERGIC NEURON TRANSPLANTATION IN THE WEAVER MOUSE MODEL OF PARKINSON’S DISEASE Edited by Lazaros C. Triarhou Volume 518 ADVANCES IN MALE MEDIATED DEVELOPMENTAL TOXICITY Edited by Bernard Robaire and Barbara F. Hales Volume 519 POLYMER DRUGS IN THE CLINICAL STAGE: Advantages and Prospects Edited by Hiroshi Maeda, Alexander Kabanov, Kazunori Kataoka, and Teruo Okano A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.
POLYMER DRUGS IN THE CLINICAL STAGE ADVANTAGES AND PROSPECTS
Edited by
Hiroshi Maeda Kumamoto University School of Medicine Kumamoto, Japan
Alexander Kabanov University of Nebraska Medical Center Omaha, Nebraska
Kazunori Kataoka University of Tokyo Tokyo, Japan
and
Teruo Okano Tokyo Women’s Medical College Tokyo, Japan
KLUWER ACADEMIC PUBLISHERS NEW YORK, BOSTON, DORDRECHT, LONDON, MOSCOW
eBook ISBN: Print ISBN:
0-306-47932-X 0-306-47471-9
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