Anaerobic Infections: Diagnosis And Management

Anaerobic Infections Anaerobic Infections Diagnosis and Management Itzhak Brook, M.D., M.Sc. Georgetown University Washington, D.C., USA Informa Healthcare USA, Inc. 52 Vanderbilt Avenue New York, NY 10017 q 2008 by Informa Healthcare USA, Inc. Informa Healthcare is an Informa business No claim to original U.S. Government works Printed in the United States of America on acid-free paper 10 9 8 7 6 5 4 3 2 1 International Standard Book Number-10: 0-8493-8257-2 (Hardcover) International Standard Book Number-13: 978-0-8493-8257-4 (Hardcover) This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequence of their use. No part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc. (CCC) 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. Library of Congress Cataloging-in-Publication Data Brook, Itzhak. Anaerobic infections : diagnosis and management / Itzhak Brook. p. ; cm. – (Infectious disease and therapy ; v. 46) Includes bibliographical references and index. ISBN-13: 978-0-8493-8257-4 (hardback : alk. paper) ISBN-10: 0-8493-8257-2 (hardback : alk. paper) 1. Anaerobic infections–Diagnosis. 2. Anaerobic infections–Treatment. I. Title. II. Series. [DNLM: 1. Bacterial Infections–diagnosis. 2. Bacteria, Anaerobic. 3. Bacterial Infections–therapy. W1 IN406HMN v.46 2007 / WC 200 B871 2007] QR201.A57B75 2007 579.3’25–dc22 Visit the Informa Web site at www.informa.com and the Informa Healthcare Web site at www.informahealthcare.com 2007020432 The book is dedicated to my wife, Joyce, my children Dafna, Tammy, Yoni, and Sara, and my granddaughter Darly. Preface Since the publication of the first edition of the book entitled Pediatric Anaerobic Infections, much has changed in our understanding and knowledge of the role of anaerobic bacteria in infections in children and adults. More clinical studies were performed describing their activity in a variety of infections, including head and neck infections, skin and soft tissue infections, abdominal and visceral abscesses, and infections after trauma. With increased awareness and early recognition, patient care improved those infections caused by these organisms. In the past three decades, resistance of anaerobic bacteria increased to many of the antimicrobials used for their ther