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15 July 2005
Vol. 309 No. 5733 Pages 337–520 $10
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When you take it off, things get interesting. Study dephosphorylation with the SignalScout™ Phosphatase Profiling System.
Immunoprecipitated PTPN12 Activity Assay
of normal cell growth. Our new SignalScout Phosphatase Profiling System* ™
allows you to study dephosphorylation by Protein Tyrosine Phosphatases (PTPs). This system includes mammalian expression clones of human PTPs and matched substrate trapping mutants. We also offer a line of highly specific antibodies against protein phosphatases to help you to detect a phosphatase of interest.
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Absorbance (405 nm)
Studying protein phosphorylation is critical to understanding the regulation
0.7 A
0.6 0.5 0.4 0.3 0.2
B,C
0.1 0.0
10
30
70
90
110
130
Time (minutes) Trendlines and data points plotted for a pNPP phosphatase assay compare the activity of SignalScout™ PTPN12 Human Phosphatase Clone