Science (vol. 309, No. 5733, July 2005)

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TeAM YYePG Digitally signed by TeAM YYePG DN: cn=TeAM YYePG, c=US, o=TeAM YYePG, ou=TeAM YYePG, [email protected] Reason: I attest to the accuracy and integrity of this document Date: 2005.07.16 12:22:31 +08'00' 15 July 2005 Vol. 309 No. 5733 Pages 337–520 $10 #/2.+(+%#6+10 %'.. $+1.1); %.10+0) /+%41#44#;5 07%.'+% #%+& #0#.;5+5 2416'+0 (70%6+10 #0 #.;5 + 5 37#06+6#6+8' 2%4 51(69#4' 51.76+105 When you take it off, things get interesting. Study dephosphorylation with the SignalScout™ Phosphatase Profiling System. Immunoprecipitated PTPN12 Activity Assay of normal cell growth. Our new SignalScout Phosphatase Profiling System* ™ allows you to study dephosphorylation by Protein Tyrosine Phosphatases (PTPs). This system includes mammalian expression clones of human PTPs and matched substrate trapping mutants. We also offer a line of highly specific antibodies against protein phosphatases to help you to detect a phosphatase of interest. Need More Information? Give Us A Call: Stratagene Europe Stratagene USA and Canada Order: 00800-7000-7000 Order: (800) 424-5444 x3 Technical Services: 00800-7400-7400 Technical Services: (800) 894-1304 Stratagene Japan K.K. Order: 03-5159-2060 Technical Services: 03-5159-2070 YYY UVTCVCIGPG EQO Absorbance (405 nm) Studying protein phosphorylation is critical to understanding the regulation 0.7 A 0.6 0.5 0.4 0.3 0.2 B,C 0.1 0.0 10 30 70 90 110 130 Time (minutes) Trendlines and data points plotted for a pNPP phosphatase assay compare the activity of SignalScout™ PTPN12 Human Phosphatase Clone