Recent Trends In Cancer Biology: Spotlight On Signaling Cascades And Micrornas: Cell Signaling Pathways And Micrornas In Cancer Biology

Sundas Fayyaz · Ammad Ahmad Farooqi Editors Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs Cell Signaling Pathways and microRNAs in Cancer Biology Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs Sundas Fayyaz  ·  Ammad Ahmad Farooqi Editors Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs Cell Signaling Pathways and microRNAs in Cancer Biology Editors Sundas Fayyaz Department of Biochemistry Rashid Latif Medical College (RLMC) Lahore, Pakistan Ammad Ahmad Farooqi Institute of Biomedical and Genetic Engineering (IBGE) Islamabad, Pakistan ISBN 978-3-319-71552-0    ISBN 978-3-319-71553-7 (eBook) https://doi.org/10.1007/978-3-319-71553-7 Library of Congress Control Number: 2018931373 © Springer International Publishing AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland Preface Cell signaling is one of the most intricate and fascinating areas of molecular biology, and it will not be wrong to say that we have witnessed groundbreaking discoveries in the era of molecular biology. It was in the late 1970s when scientists started to discover interwoven network of proteins. Genetic, genomic, and proteomic studies have improved our understanding of these highly synchronized, hierarchically assembled arrays of proteins, which transduce the signals linearly and also cross-talk with other signaling cascades. This book comprehensively reviews most recent advancements in our understanding of the involvement of intracellular signaling cascades in cancer development and progression. Detailed information presented in this book will help y