Biochemistry

STRUCTURE AND BONDING Volume 23 Editors: J.D. Dunitz, Ziirich P. Hemmerich, Konstanz • R. H. Holm, Cambridge J. A. Ibers, Evanston • C. K. Jorgensen, Gen~ve J. B. Neilands, Berkeley • D. Reinen, Marburg R. J. P. Williams, Oxford With 50 Figures Springer-Verlag New York Heidelberg Berlin 1975 ISBN 0-387-07332-9 Springer-Verlag New York Heidelberg Berlin ISBN 3-540-07332-9 Springer-Verlag Berlin Heidelberg New York Library of Congress Catalog Card Number 6%11280 This work is subiect to copyright. All rights are reserved, whether the whole or part of the material is concerned specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under § 54 of the German Copyright Law where copies are made for other then for private use, a fee is payable to the publisher, the amount of the fee to be determined by agreement with the publisher. © by Springer-Verlag Berlin Heidelberg 1975 Printed in Germany The use of general descriptive names, trade marks, etc. in this publication, even if the former are not especially identified, is not to be taken as a sign that such names, as understood by the Trade Marks and Merchandise Marks Act, may accordingly be used freely by anyone. Typesetting and printing: Meister-Druck, Kassel. Bookbinding: Br~hlsche Universit~tsdruckerei, Gie/~en Contents Copper Proteins - - Systems Containing the "Blue" Copper Center James A. Fee Mechanisms of Zinc Ion Catalysis in Small Molecules and Enzymes Michael F. Dunn 61 Kinetics and Mechanism of Metalloporphyrin Formation Walter Schneider 123 Hydrogen-Deuterium Exchange in Aromatic Compounds Milton 0rchin and Donald M. Bollinger 167 STRUCTURE AND BONDING is issued at irregular intervals, according to the material received. With the acceptance for publication of a manuscript, copyright of all countries is vested exclusively in the publisher. Only papers not previously published elsewhere should be submitted. Likewise, the author guarantees against subsequent publication elsewhere. The text should be as clear and concise as possible, the manuscript written on one side of the paper only. Illustrations should be limited to those actually necessary. Manuscripts will be accepted by the editors: Professor Dr. fade. D. Dunitz Laboratorium ftir Organische Chemie der Eidgen6ssischen Hochschule CH-8006 Ztirich, Universit~tsstraBe 6/8 Professor Dr. Peter Hemmerich Universit~it Konstanz, Fachbereich Biologie D-7750 Konstanz, Postfach 733 Professor Richard H. Holm Department of Chemistry, Massachusetts Institute of Technology Cambridge, Massachusetts 02139/U.S.A. Professor fames A . Ibers Department of Chemistry, Northwestern University Evanston, lllinois 60201/U.S.A. Professor Dr. C. Klixbiill forgensen 51, Route de Frontenex, CH-1207 Gen~ve Professor foe B. Neilands University of California, Biochemistry Department Berkeley, California 94720/U.S.A. Professor Dr. Dirk Reinen Fachbereich Chemie der Universit~it Marburg D-3550 Marburg, GutenbergstraBe 18 Professor Robert foseph P. Williams Wadham College, Inorganic Chemistry Laboratory Oxford OX1 3QR/Great Britain SPRINGER-VERLAG NEW YORK INC. SPRINGER-VERLAG D-6900 Heidelberg 1 P. O. Box 105280 Telephone (06221) 487.1 Telex 04-61723 D-1000 Berlin 33 Heidelberger Platz 3 Telephone (030) 822001 Telex 01-83319 175, Fifth Avenue New York, N. Y. 10010 Telephone 673-2660 Copper Proteins Systems Containing the "Blue" Copper Center James A. F e e B i o p h y s i c s R e s e a r c h Division,* I n s t i t u t e of Science a n d Te c hnol ogy, U n i v e r s i t y of Michigan