E-Book Content
DEVELOPMENTS IN TOXICOLOGY AND ENVIRONMENTAL SCIENCE Volume 1 —Clinical Chemistry and Chemical Toxicology of Metals, edited by S. S. Brown, 1977 Volume 2—Progress in Genetic Toxicology, edited by D. Scott, B.A. Bridges, and F. H. Sobels, 1977 Volume 3—Chemical Toxicology of Food, edited by C. L. Galli, R. Paoletti, and G. Vettorazzi, 1978 Volume 4—Toxicology and Occupational Medicine, W. B. Deichmann (Organizer), 1979
TOXICOLOGY AND OCCUPATIONAL MEDICINE Proceedings of the Tenth Inter-American Conference on Toxicology and Occupational Medicine, Key Biscayne (Miami), Florida, October 22-25,1978
Organizer: WILLIAM B. DEICHMANN, PhD, MD (hon) University of Miami School of Medicine, Miami, Florida, USA
ELSEVIER/NORTH-HOLLAND NEW YORK · AMSTERDAM · OXFORD
©1979 by Elsevier North Holland, Inc. with the exception of those articles authored by Kolbye (pp. 9-18), Haas (pp. 31-43), Kraybill (pp. 61-70), Cueto and Chu (pp. 99-108), Cox and Irving (pp. 221-228), Jackson, Frith, West and Stanley (pp. 233-242), Baier (pp. 253-260), L. F. Stickel, W. H. Stickel, R. D. McArthur and D. L Hughes (pp. 387-396), and William H. Stickel, William L Reichel, and Donald L Hughes (pp. 397-406) which are works of the United States Government. Published by Elsevier North Holland, Inc. 52 Vanderbilt Avenue, New York, New York 10017 Sole distributors outside the U.S.A. and Canada: Elsevier/North-Holland Biomedical Press 335 Jan van Galenstraat, P. 0. Box 211 Amsterdam, The Netherlands Library of Congress Cataloging in Publication Data Inter-American Conference on Toxicology and Occupational Medicine, 10th, Miami, Fla. Toxicology and occupational medicine. (Developments in toxicology and environmental science; 4) Bibliography: p. Includes index. 1. Toxicology—Congresses. 2. Industrial toxicology—Congresses. 3. Carcinogens—Congresses. I. Deichmann, William B. II. Title. III. Series. [DNLM: 1. Industrial medicine—Congresses. 2. ToxicologyCongresses. W1 DE998T v. 4 / WA65 I56 1978t] RA1191.157 978 616.9Ό4Ό71 78-10198 ISBN 0-444-00288-X Manufactured in the United States of America
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Preface
The papers in this volume were presented at the 10th Inter-American Conference on Toxicology and Occupational Medicine of the University of Miami, conducted from October 22 to 25, 1978 at the Key Biscayne Hotel, Miami, Florida This hotel is located on the ocean side of the secluded tropical island of Key Biscayne, 15 minutes by car from downtown Miami,
Each author accepted editorial responsibility for his report. The purpose of the 10th Conference, as in previous conferences, was the presentation by delegates of research reports on subjects in the broad field of Toxicology and Occupational Medicine, followed by free discussions by all participants. The Conference met the specific requirements of the American Medical Association, and of the Florida Medical Association for 16 credit hours: "As an organization accredited for continuing Medical Educa tion, the University of Miami School of Medicine certifies that this continuing Medical Education Activity meets the criteria for sixteen hours in Category One of the Physician's Recognition Award of the American Medical Association. - Florida Medical Association, mandatory hours - sixteen".
Delegates attended from the United States, from Buenos Aires (Argentina), Porto Alegre, Salvador - Bahia, Sao Paulo, and Rio de Janiero (Brazil), Ottawa, Montreal and Toronto (Canada), London and Manchester (England), Takoradi (Ghana), and The Hague (Netherlands).
The Conference honored Florida Congressman Dante Fascell who has "vigorously pursued the Good Neighbor Policy with countries of this hemisphere and who has won the admiration and respect of all of us", and Dr. H.G.S. van Raalte "for his pioneering and outstanding contributions in the field of Toxicology and Occupational Me