Animal Cell Technology: Basic & Applied Aspects: Proceedings Of The Thirteenth Annual Meeting Of The Japanese Association For Animal Cell Technology (jaact), Fukuoka-karatsu, November 16–21, 2000

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Animal cell technology is a growing discipline of cell biology, which aims not only to understand structures, functions, and behaviours of differentiated animal cells but also to ascertain their ability to be used for industrial and medical purposes. The goal of animal cell technology includes accomplishments of clonal expansion of differentiated cells with useful ability, optimisation of their culture conditions, modulation of their ability for production of medically and pharmaceutically important proteins, and the application of animal cells to gene therapy, artificial organs, and functional foods. This volume gives the reader a complete review of the present state of the art in Japan and other countries where this field is well advanced. The Proceedings will be useful for cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers, and other disciplines related to animal cell culture, working in either academic environments or in industries of biotechnology and pharmacy.


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ANIMAL CELL TECHNOLOGY: BASIC & APPLIED ASPECTS Volume 12 Animal Cell Technology: Basic & Applied Aspects Volume 12 Proceedings of the Thirteenth Annual Meeting of the Japanese Association for Animal Cell Technology (JAACT), Fukuoka-Karatsu, November 16-21, 2000 edited by SANETAKA SHIRAHATA KIICHIRO TERUYA and YOSHINORI KATAKURA Department of Genetic Resources Technology, Faculty ofAgriculture, Kyushu University, Fukuoka, Japan SPRINGER-SCIENCE+BUSINESS MEDIA, B.V. A C.I.P. Catalogue record for this book is available from the Library of Congress. ISBN 978-90-481-5934-5 ISBN 978-94-017-0728-2 (eBook) DOI 10.1007/978-94-017-0728-2 Printed on acid-free paper Ali Rights Reserved © 2002 Springer Science+Business Media Dordrecht Originally published by Kluwer Academic Publishers in 2002 No part of the material protected by this copyright notice may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording or by any information storage and retrieval system, without written permission from the copyright owner. Contents Preface XV Symposium Approaches to Human Gene Therapy for Next Century Improvement of adenovirus vectors for gene transfer H. Mizuguchi, T. Hayakawa Gene therapy for genetic disease and cancer R. S. Mcivor 7 Application of Chip Technology in Molecular and Cellular Biology Gene expression profiling of mouse postnatal cerebellar development Adaptor-tagged competitive PCR and its application to the mammalian nervous system K. Katoh 13 Mesenchymal Stem Cells for Reconstructive Surgery Generation of regenerated cardiomyocytes and its therapeutic use for cell transplantation into failing heart K. Fukuda 19 Advanced Functional Foods and Water for Prevention of Diseases Reduced water for prevention of diseases S. Shirahata 25 Clinical applications of electrolyzed-reduced water H. Hayashi, M. Kawamura 31 Molecular Biology of Fish Cells in vitro Identification and characterization offibronectin isoforms from zebrafish Q. Zhao, X. Liu, P. Collodi 37 vi Neurogenesis in zebrafish embryo cell cultures N. N. Singh, D. Barnes 43 Search for Bioactive Substances Using Animal Cells (Satellite Symposium Karatsu) Assay systems for screening food factors that have anti-proliferative and antiinvasive potential using rat ascites hepatoma cells in culture Y. Miura, K. Yagasaki 51 Search for chemopreventive agents on the basis of the involvement of oxidative stress and inflammation in carcinogenesis A. Murakami, Y. Nakamura, K. Koshimizu, H. Ohigashi 57 Functional analysis ofsphingolipids using a specific en
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