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Written by an experienced clinician and researcher in the field, this reference provides practical information on the clinical recording techniques, physiologic origins, and applications of electroretinogram (ERG), electro-oculogram (EOG), and visual evoked potential (VEP) tests.
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Electrophysiology of Vision Clinical Testing and Applications
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Electrophysiology of Vision Clinical Testing and Applications
Byron L. Lam Bascom Palmer Eye Institute University of Miami School of Medicine, Florida, U.S.A.
Although great care has been taken to provide accurate and current information, neither the author(s) nor the publisher, nor anyone else associated with this publication, shall be liable for any loss, damage, or liability directly or indirectly caused or alleged to be caused by this book. The material contained herein is not intended to provide specific advice or recommendations for any specific situation. Trademark notice: Product or corporate names may be trademarks or registered trademarks and are used only for identification and explanation without intent to infringe. Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress. ISBN: 0-8247-4068-8 This book is printed on acid-free paper. Headquarters Marcel Dekker, 270 Madison Avenue, New York, NY 10016, U.S.A. tel: 212-696-9000; fax: 212-685-4540 Distribution and Customer Service Marcel Dekker, Cimarron Road, Monticello, New York 12701, U.S.A. tel: 800-228-1160; fax: 845-796-1772 World Wide Web http:==www.dekker.com The publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales=Professional Marketing at the headquarters address above. Copyright # 2005 by Marcel Dekker. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher. Current printing (last digit): 10
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Preface
This book was written to provide the clinician with practical information of visual electrophysiologic tests in an accessible and understandable format. Personnel involved in electrophysiologic testing and ophthalmic trainees may also find this book beneficial. The book is organized into two sections keeping in mind that the majority of clinical users of visual electrophysiologic tests do not perform the tests themselves. The first section consists of six chapters that discuss clinical recording techniques and physiologic origins of electroretinogram (ERG), electro-oculogram (EOG), and visual evoked potential (VEP); the section ends with a chapter that focuses on the effects of maturation and aging on these tests as well as electrophysiologic testing in infants. The second section consists of 11 chapters dealing with the clinical applications of ERG, EOG, and VEP testing. The first chapter of this section is an overview from a clinical perspective. The electrophysiologic findings of specific clinical conditions are discussed in subsequent chapters with an emphasis on when and why a specific test should be considered. The clinician iii
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will find the second section particularly useful in everyday patient care. ACKNOWLEDGMENTS The completion of the book wouldn’t have been possible without the support of my family and colleagues. Dr. Mu Liu assisted immensely in many of the figures and tables. Rick Stratton helped substantially in the preparation of figures.