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Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany.
Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes.
Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics:
- Structure and function of dipeptidyl aminopeptidases, - DPP IV-like proteins, - Immune mechanisms and immune disorders, - Cancer and angiogenesis, - Diabetes and metabolism, - Therapeutic implications.
E-Book Content
DIPEPTIDYL AMINOPEPTIDASES IN HEALTH AND DISEASE
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan
Recent Volumes in this Series Volume 515 NEUROPILIN: From Nervous System to Vascular and Tumor Biology Edited by Dominique Bagnard Volume 516 TRIPLE REPEAT DISEASES OF THE NERVOUS SYSTEM Edited by Lubov T. Timchenko Volume 517 DOPAMINERGIC NEURON TRANSPLANTATION IN THE WEAVER MOUSE MODEL OF PARKINSON’S DISEASE Edited by Lazaros C. Triarhou Volume 518 ADVANCES IN MALE MEDIATED DEVELOPMENTAL TOXICITY Edited by Bernard Robaire and Barbara F. Hales Volume 519 POLYMER DRUGS IN THE CLINICAL STAGE: Advantages and Prospects Edited by Hiroshi Maeda, Alexander Kabanov, Kazurori Kataoka, and Teruo Okano Volume 520 CYTOKINES AND AUTOIMMUNE DISEASE Edited by Pere Santamaria Volume 521 IMMUNE MECHANISMS IN PAIN AND ANALGESIA Edited by Halina Machelska and Christoph Stein Volume 522 NOVEL ANGIOGENIC MECHANISMS: Role of Circulating Progenitor Endothelial Cells Edited by Nicanor I. Moldovan Volume 523 ADVANCES IN MODELLING AND CLINICAL APPLICATION OF INTRAVENOUS ANAESTHESIA Edited by Jaap Vuyk and Stefan Schraag Volume 524 DIPEPTIDYL AMINOPEPTIDASES IN HEALTH AND DISEASE Edited by Martin Hildebrandt, Burghard F. Klapp, Torsten Hoffmann, and Hans-Ulrich Demuth
A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.
DIPEPTIDYL AMINOPEPTIDASES IN HEALTH AND DISEASE Edited by
Martin Hildebrandt, Burghard F. Klapp Medical Faculty Charité, Humboldt University Berlin Berlin, Germany
Torsten Hoffman and Hans-Ulrich Demuth Probiodrug SG Halle (Saale), Germany
KLUWER ACADEMIC PUBLISHERS NEW YORK, BOSTON, DORDRECHT, LONDON, MOSCOW
eBook ISBN: Print ISBN:
0-306-47920-6 0-306-47717-3
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Contributors
Catherine A. Abbott School of Biological Sciences, Flinders University, GPO Box 2100, Adelaide SA 5001,