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MIGUEL MAROTO, PhD, is a MRC Career Development Fellow and Lecturer at the University of Dundee, UK. He received his PhD in Biochemistry and Molecular Biology from the Department of Biochemistry of the Universidad Autonoma of Madrid, Spain. His research interests include investigating the biochemical basis of different signalling mechanisms implicated in the acquisition of specific cell fates during vertebrate development. During the last years he has been implicated in the analysis of the mechanism of the molecular clock involved in the control of the process of somitogenesis.
NICK MONK, PhD, is an Associate Professor and Reader in Applied Mathematics at the University of Nottingham, UK. Having received his Ph.D. in theoretical physics from the University of London, his research changed focus to centre on the mathematical and computational modelling of biological systems. Particular areas of interest include pattern formation, developmental biology, complex network dynamics and mechanisms of intercellular signalling.
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Cellular Oscillatory Mechanisms
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University ofNew York at Buffalo IRUN R. COHEN, The Weizmann Institute ofScience ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research JOHN D. LAMBRIS, University ofPennsylvania RODOLFO PAOLETTI, University ofMilan
Recent Volumes in this Series Volume 633 CROSSROADS BETWEEN INNATE AND ADAPTIVE IMMUNITY II Edited by Stephen P. Schoenberger, Peter D. Katsikis, and Bali Pulendran Volume 634 HOT TOPICS IN INFECTION AND IMMUNITY IN CHILDREN V Edited by Adam Finn, Nigel Curtis, and Andrew J. Pollard Volume 635
or MICROBIOTAAND REGULATION OF THE IMMUNE SYSTEM Edited by Gary B. Huffuagle and Mairi Noverr Volume 636 MOLECULAR MECHANISMS IN SPERMATOGENESIS Edited by C. Yan Cheng Volume 637 MOLECULAR MECHANISMS IN XERODERMA PIGMENTOSUM Edited by Shamin Ahmad and Fumio Hanaoka Volume 638 SOMITOGENESIS Edited by Mignel Maroto and Neil Whitlock Volume 639 BREAST FEEDING: EARLY INFLUENCES ON LATER HEALTH Edited by Gail Goldberg Volume 640 MULTICHAIN IMMUNE RECOGNITION RECEPTOR SIGNALING Edited by Alexander Sigalov Volume 641 CELLULAR OSCILLATORY MECHANISMS Edited by Mignel Maroto and Nicholas A.M. Monk
A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.
Cellular Oscillatory Mechanisms Edited by Miguel Maroto College ofLife Sciences, University ofDundee, Dundee, Scotland, UK
Nicholas A.M. Monk School ofMathematical Sciences, University ofNottingham, Nottingham, UK
Springer Science+Business Media, LLC Landes Bioscience / Eurekah
Springer Science+Business Media, LLC Landes Bioscience
Copyright ©2008 Landes Bioscience and Springer Science+Business Media, LLC All rights reserved. No part ofthis book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system; for exclusive use by the Purchaser of the work. Printed in the USA. Springer Science+Business Media, LLC, 233 Spring Street, New York, New York 10013, USA http://www.springer.com Please address all inquiries to the Publishers: Landes Bioscience, 1002 West Avenue, Austin, Texas 7870 I, USA Phone: 512/6376050; FAX: 512/637 6079 http://www.landesbioscience.com Cellular Oscillatory Mechanisms edited by Miguel Maroto and Nicholas A.M. Monk, Landes Bioscience 1 Springer Science+Business Me