HANDBOOK OF ISOLATION AND CHARACTERIZATION OF IMPURITIES IN PHARMACEUTICALS This is Volume 5 of SEPARATION SCIENCE AND TECHNOLOGY A reference series edited by Satinder Ahuja HANDBOOK OF ISOLATION AND CHARACTERIZATION OF IMPURITIES IN PHARMACEUTICALS Edited by Satinder Ahuja Ahuja Consulting Calabash, NC Karen Mills Alsante Pfizer, Inc. Groton, CT Amsterdam Boston London New York Oxford San Francisco Singapore Sydney Tokyo Paris San Diego Academic Press An imprint of Elsevier Science 525 B Street, Suite 1900 San Diego, California 92101-4495 ß 2003 Elsevier Science (USA) All rights reserved. This work is protected under copyright by Elsevier Science, and the following terms and conditions apply to its use: Photocopying Single photocopies of single chapters may be made for personal use as allowed by national copyright laws. Permission of the Publisher and payment of a fee is required for all other photocopying, including multiple or systematic copying, copying for advertising or promotional purposes, resale, and all forms of document delivery. Special rates are available for educational institutions that wish to make photocopies for non-profit educational classroom use. Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail:
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