Advances in VIRUS RESEARCH VOLUME 11 CONTRIBUTORS TO THIS VOLUME R. BERCKS J. BRANDES FRANCIS 0. HOLMES HERBERTS. IIURLBUT IRVINGRAPPAPORT IRVINGR. SCIINEIDJCR ALBERTSIEGEL J. T. SLYKHUIS KENNETHM. SMITH PETERK. VOGT Advances in VIRUS RESEARCH Edited by KENNETH M. SMITH MAX A. LAUFFER Department of Botany University of Texas Austin, Texas Department of Biophysics University of Pittsburgh Pittsburgh, Pennsylvania VOLUME 11 1965 ACADEMIC PRESS NEW YORK AND LONDON COPYRIGHT @ 1965, BY ACADEMICPRESSINC. ALL RIGHTS RESERVED. NO PART OF THIS BOOK MAY nE nwno~ucm IN ANY mnM, I1Y PIIOTOSTAT, MICROFILM, OR ANY OTHER MEANS, WITHOUT WRITTEN PEHMISSION FHOM THE PUDLISIIERS. ACADEMIC PRESS INC. 111 Fifth Aveniie, New York, New York 10003 7Jnited Kingdom Edition pzihlished by ACADEMIC PRESS I N C . ( L O N D O N ) LTD. Berkeley Square House, London W.l LIBRARY OF CONGRESS CATALOG CARD PRINTED I N TIIE UNITED STATES OF AMERICA NUMBER:53-11559 CONTRIBUTORS TO VOLUME 1 1 Numbers in parentheses indicate the pages on which the authors’ contributions begin. R. BERCKS,Biologische Bundesamtalt fur Land- und Forstwirtschaft, Institut fur Virusserologie, Braunschweig, Germany ( 1 ) J. BRANDES,Biologische Bundesanstalt fur Land- und Forstwirtschuft, Institut fur landwirtschaftliche Virusforschung, Braunschweig, Germany ( 1 ) FRANCIS 0. HOLMES,The Rockefeller Institute, New York, New York (139 ) HERBERTS. HURLBUT,Nraval Medical Research Institute, Bethesda, Maryland (277) IRVINGRAPPAPORT, Department of Microbiology, New York Medical College, New York, New York (223) IRVINGR. SCHNEmER, P h a t Virology Laboratory, Crops Research Division, U.S. Department of Agriculture, Beltsville, Maryland (163) ALBERTSEIGEL,Department of Agricultural Biochemistry, University of Arizona, Tucson, Arizona (25) J. T. SLYKHUIS, Plant Research Institute, Canada Department of
[email protected], Ottawa, Canada (97) KENNETH M. SMITH,*Department of Biophysics, University of Pittsburgh, Pittsburgh, Pcnnsylvania (61 ) PETER K. VOGT, Department of Pathology, University o f Colorado Medical School, Denver, Colorado (293) * Present nddress: Cell Research Institute, Department of Botany, University of Texas, Austin, Texas. V This Page Intentionally Left Blank CONTENTS CONTRIBUTORS TO VOLUME11 . . . . . . . . . . . . . . v Gross Morphology and Serology as a Basis for Classification of Elongated Plant Viruses J . BRANDESAND R . BERCKS I. Introduction . . . . . . . . . . . . . . I1 Relationship and Classification . . . . . . . . I11 Morphology of Elongated Plant Viruses . . . . . . IV . Serology of Elongated Plant Viruses . . . . . . . V Combination of Morphological Data and Serological Results VI . Additional Characteristics and Classification . . . . VII . Taxonomic Assessment and Nomenclature . . . . . VIII Conclusions . . . . . . . . . . . . . . References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2 3 7 12 18 20 22 22 Artificial Production of Mutants of Tobacco Mosaic Virus ALBERTSIEGEL 1. Introduction . . . . . . . . . . . I1 Techniques for Detecting and Isolating Variants I11. Induction of TMV Mutants . . . . . . IV . The TMV Genome . . . . . . . . V TMV Mutants and the Genetic Code . . . VI Discussion and Summary . . . . . . . References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 26 31 44 45