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This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been brought to light. Reports on these developments have been put together in this book, Bacterial Signal Transduction: Networks and Drug Targets. The aim of this book is to provide an incentive for graduate students, academic scientists, and researchers in the pharmaceutical industry to further elucidate the TCS networks and apply them in the search for novel drugs.
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Bacterial Signal Transduction: Networks and Drug Targets ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University ofN~ York at Buffalo IRUN R. COHEN, The Weizmann Institute ofScience ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research JOHN D. LAMBRIS, University ofPennsylvania RODOLFO PAOLETTI, University ofMilan Recent Volumes in this Series Volume 623 ALTERNATNE SPLICING IN THE POSTGENOMICERA Edited by BenjaminJ. Blencoweand Brenton R. Graveley Volume624 SUNLIGHT,VITAMIND AND SKIN CANCER Edited by Jorg Reiehrath Volume625 DRUG TARGETSIN KINETOPLASTID PARASITES Edited by Hemanta K. Majumder Volume626 GENOMIC IMPRINTING Edited by Jon F. Wilkins Volume627 TRANSGENESISAND THE MANAGEMENTOF VECTOR-BORNE DISEASE Edited by Scrap Aksoy Volume628 BRAIN DEVELOPMENTIN DROSOPHILAMELANOGASTER Edited by Gerhard M. Technau Volume 629 PROGRESS IN MOTORCONTROL Edited by Dagmar Sternad Volume630 INNOVATNE ENDOCRINOLOGY OF CANCER Edited by Lev M. Berstein and Richard 1. Santen Volume631 BACTERIALSIGNALTRANSDUCTION Edited by Ryutaro Utsumi A Continuation OrderPlanis available for this series. Acontinuation orderwillbringdelivery of each new volume immediately uponpublication. Volumes are billedonly uponactualshipment. For further information pleasecontactthepublisher. Bacterial Signal Transduction: Networks and Drug Targets Edited by Ryutaro Utsumi, PhD Department ofBioscience, Graduate School ofAgriculture, Kinki University, Nakamachi, Nara, Japan Springer Science+Business Media, LLC Landes Bioscience Springer Science+Business Media, LLC Landes Bioscience Copyright ©2008 Landes Bioscience and Springer Science+Business Media, LLC All rights reserved. No part ofthis book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system; for exclusive use by the Purchaser of the work. Printed in the USA Springer Science+Business Media, LLC, 233 Spring Street, New York, New York 10013, USA http://www.springer.com Please address all inqniries to the publishers: Landes Bioscience, 1002 West Avenue, 2nd Floor, Austin, Texas 7870 I, USA Phone: 512/6376050; FAX: 512/6376079 http://www.landesbioscience.com Bacterial Signal Transduction: Networks and Drug Targets edited by Ryutaro Utsumi, Landes Bioscience / Springer Science+Business Media, LLC dual imprint / Springer series: Advances in Experimental Medicine and Biology. ISBN: 978-0-387-78884-5 While the authors, editors and publisher believe that drug selection and dosage and the specificatious and usage of equipment and devices, as set forth in this book, are in accord with current recommendations and practice at the time of publication, they make no warranty, expressed or implied, with respect to material described in this book. In view of the ongoing research, equipment development, changes in governmental regulations and the rapid accumulation ofinformation relating to the bi