OCULAR THERAPEUTICS EYE ON NEW DISCOVERIES This publication has been supported by Alcon Research, Ltd. OCULAR THERAPEUTICS EYE ON NEW DISCOVERIES Edited by T HOMAS Y ORIO , Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, Texas, USA A BBOT F. C LARK Alcon Research Ltd, Fort Worth, Texas, USA M ARTIN B. W AX Alcon Research Ltd, Fort Worth, Texas, USA AMSTERDAM • BOSTON • HEIDELBERG • LONDON • NEW YORK • OXFORD PARIS • SAN DIEGO • SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO Academic Press is an imprint of Elsevier Academic Press is an imprint of Elsevier 360 Park Avenue South, New York, NY 10010-1710 84 Theobald’s Road, London WC1X 8RR, UK 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA 525 B Street, Suite 1900, San Diego, California 92101-4495, USA First edition 2008 Copyright © 2008 Elsevier Ltd. All rights reserved No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email:
[email protected] Alternatively you can submit your request online by visiting the Elsevier web site at http://elsevier. com/locate/permissions, and selecting Obtaining permission to use Elsevier material Notice No responsibility is assumed by the publisher for any injury and/or damage to persons or prope