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Editors Michael Cooke Royal Holloway, University of London, Centre for Chemical Sciences Egham Hill, Egham, Surrey TW20 0EX, UK Colin F. Poole Wayne State University, Department of Chemistry, Detroit MI 48202, USA Editor-in-Chief Ian D. Wilson AstraZeneca Pharmaceuticals Limited, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK Managing Technical Editor Edward R. Adlard Formerly of Shell Research Limited, Thornton Research Centre, PO Box 1, Chester CH1 3SH, UK vi EDITORIAL ADVISORY BOARD Editorial Advisory Board Richard W. Baker Membrane Technology & Research Inc (MTR) 1360 Willow Road, Suite 103 Menlo Park CA 94025, USA Kenneth Jones Affinity Chromatography Limited Freeport Ballsalla Isle of Man, UK Kenneth L. Busch Kennesaw State University Office of Sponsored Programs 1000 Chastain Road Kennesaw GA 30144, USA Chris Lowe University of Cambridge Institute of Biotechnology Tennis Court Road Cambridge, UK Howard A. Chase University of Cambridge Department of Chemical Engineering Pembroke Street Cambridge CB2 3RA, UK Jan Cilliers University of Science and Technology in Manchester Department of Chemical Engineering PO Box 880 Manchester M60 1QD, UK Alan Dyer University of Salford School of Sciences, Cockroft Building Salford M5 4WT, UK Heinz Engelhardt UniversitaK t des Saarlandes Instrumentelle Analytik/Umweltanalytik Postfach 15 11 50 66041 Saarbruecken, Germany William F. Furter Royal Military College of Canada Department of Chemical Engineering Kingston Ontario K7K 5L0, Canada Josef Janca UniversiteH de La Rochelle Pole Sciences et Technologie Equipe de Physico-Chimie Macromoleculaire Avenue Michel Crepeau I 17042 La Rochelle, France Walt Jennings J&W Scientific Incorporated 91 Blue Ravine Road Folsom CA 95630, USA David Perrett St Bartholomew’s and the Royal London School of Medicine an