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Volume 437 Number 7060 pp789-926 In this issue (6 October 2005) • • • • • • • • Editorials Research Highlights News News Features Business Correspondence • • • • • • Books and Arts Essay News and Views Brief Communications Articles Letters Naturejobs Futures Editorials Reaching for the Moon p789 Naive or not, NASA's next shot at landing on the Moon can succeed only if it is launched as a genuinely international collaboration. In need of rehab p789 The reputation of one of the world's most respected regulatory agencies is on the wane. Welcome Nature Physics p790 The launch of a new Nature journal comes at an exciting time for physics. Research Highlights Research highlights p792 News The 1918 flu virus is resurrected p794 The recreation of one of the deadliest diseases known could help us to prevent another pandemic. Or it might trigger one, say critics. Andreas von Bubnoff investigates whether the benefits outweigh the risks. Sidelines p796 Japan jumps towards personalized medicine p796 Desktop-device uses advanced DNA chip to analyse patient's blood. David Cyranoski Q marks the spot as ancient sculptures yield their origins p797 Hopes raised that discovery will save Mayan site from local destruction. Alexandra Witze Electric current captures top sperm p799 Technique leads to birth of healthy baby after other methods fail. Carina Dennis Australia mooted as dump for world's nuclear waste p799 Former prime minister suggests uranium by-products could subsidize environmental projects. Carina Dennis Physics prize puts spotlight on optics p800 Understanding quantum nature of light led to breakthroughs. Jim Giles California prepares to roll out stem-cell funding p800 Cash may soon be flowing despite legal challenges. Rex Dalton Gut feeling secures medical Nobel for Australian doctors p801 Microbiologists win for proving link between bacteria and stoma