Stem Cell Factor Jonathan Roy Keller1,* and Diana Marie Linnekin2 1 Intramural Research and Support Program-SAIC, Frederick Cancer Research and Development Center-NCI, Building 560, Room 12-03, PO Box B, Frederick, MD 21702-1201, USA 2 Basic Research Laboratory-DBS, Frederick Cancer Research and Development Center-NCI, Building 567, PO Box B, Frederick, MD 21702-1201, USA * corresponding author tel: 301-846-1461, fax: 301-846-6646, e-mail:
[email protected] DOI: 10.1006/rwcy.2000.09003. SUMMARY Stem cell factor (SCF) and its receptor, c-Kit, are essential for hematopoietic, melanocyte, and germ cell development. In the hematopoietic compartment, SCF has been shown to act on cells at multiple stages of development, including ef