Comprehensive Natural Products Ii: Chemistry And Biology: Natural Products Structural Diversity-ii Secondary Metabolites Sources, Structures And Chemical Biology

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E-Book Overview

This work presents a definitive interpretation of the current status of and future trends in natural products-a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999).* Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine * Stimulates new ideas among the established natural products research community-which includes chemists, biochemists, biologists, botanists, and pharmacologists * Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats  

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E-Book Information

• Volume Info: Volume 2

• Year: 2,010

• Edition: 1

• Pages: 689

• Pages In File: 689

• Language: English

• Issue: до 2011-08

• Identifier: 0080453813,9780080453811

• Org File Size: 37,403,352

• Extension: pdf

• Toc: 1 CONAP_Contents_all_volumes......Page 1Overview and Introduction......Page 13Terrestrial Plants as a Source of Novel Pharmaceutical Agents......Page 17Vinca Alkaloids......Page 18Podophyllotoxin, Etoposide, and Teniposide......Page 19Camptothecin and Analogues......Page 20Combretastatins......Page 21Taxol and Its Analogues......Page 22Plant Saponins......Page 25Triptolide......Page 26Ingenol-3-Angelate (PEP005)......Page 27Flavopiridol......Page 28Adenine Derivatives: Olomucine, Roscovitine, and Analogues......Page 29Other Active Compounds in Preclinical Development......Page 30Michellamine B......Page 34The Calanolides......Page 35Betulinic Acid......Page 36Quinine......Page 37Resveratrol......Page 38Hoodia Compounds......Page 39Digoxin and Related Cardiac Glycosides......Page 40Huperzine A......Page 41St. John’s Wort......Page 42Salvinorin A......Page 43References......Page 44Introduction......Page 52Isoprenoids......Page 53Labdanes......Page 54Dactylomelane metabolites......Page 55Meroditerpenes......Page 56Chemical Ecology......Page 57Antiherbivore metabolites......Page 58Antimicrobial metabolites......Page 59Polyether triterpenes......Page 60Dolabellanes......Page 61Fatty Acid and Polyketide Metabolites......Page 62C15 acetogenins......Page 63Manauealides......Page 64Furanones......Page 65Halogenated Phenols......Page 66Depsipeptides......Page 67Alkaloid Metabolites......Page 682,7-Naphthyridines......Page 69Glycolipids......Page 70Abbreviations......Page 72References......Page 73Introduction......Page 77Challenges in Arthropod Natural Products Chemistry......Page 80Monoterpenes......Page 81Sesquiterpenes and Diterpenes......Page 83Steroids and Triterpenes......Page 85Fatty Acid and Other Polyacetate Derivatives......Page 88Fatty Acid-Amino Acid Conjugates and Related Elicitors......Page 91Bicyclic Acetals and