Hot Topics In Infection And Immunity In Children Vii

Advances in Experimental Medicine and Biology Volume 697 Editorial Board: IRUN R. COHEN, The Weizmann Institute of Science ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research JOHN D. LAMBRIS, University of Pennsylvania RODOLFO PAOLETTI, University of Milan For further volumes: http://www.springer.com/series/5584 Nigel Curtis · Adam Finn · Andrew J. Pollard Editors Hot Topics in Infection and Immunity in Children VII 13 Editors Nigel Curtis, Ph.D. Department of Paediatrics University of Melbourne Parkville, VIC 3052, Australia Adam Finn, Ph.D. Institute of Child Life and Health University of Bristol BS2 8AE, Bristol, UK Andrew J. Pollard Oxford Vaccine Group University of Oxford OX3 9DU, Oxford, UK ISSN 0065-2598 ISBN 978-1-4419-7184-5 e-ISBN 978-1-4419-7185-2 DOI 10.1007/978-1-4419-7185-2 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2010935651 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Preface Each of the chapters in this book is based on a lecture given at the seventh ‘Infection and Immunity in Children’ (IIC) course held at the end of June 2009 at Keble College, Oxford. Thus, it is the seventh book in a series, which collectively provide succinct and readable updates on just about every aspect of the discipline of Paediatric Infectious Diseases. The eighth course (28–30 June 2010) has another exciting programme delivered by renowned top-class speakers, and an eighth edition of this book will duly follow. The clinical discipline of Paediatric Infectious Diseases continues to grow and flourish in Europe. The University of Oxford Diploma Course in Paediatric Infectious Diseases, started in 2008, is now well established with a large number of trainees enrolled from all parts of Europe. The Oxford IIC course, as well as other European Society for Paediatric Infectious Diseases (ESPID)-sponsored educational activities, is an integral part of this course. We hope this book will provide a further useful contribution to the materials available to trainees and practitioners in this important and rapidly developing field. Melbourne, Australia Bristol, UK Oxford, UK Nigel Curtis Adam Finn Andrew J. Pollard v Acknowledgments We thank all the contributors who have written chapters for this book, which is based on lectures given at the 2009 Infection and Immunity in Children (IIC) course. We are grateful to the staff o