SERIES EDITORS KARL MARAMOROSCH Rutgers University, New Jersey, USA AARON J. SHATKIN Center for Advanced Biotechnology and Medicine, New Jersey, USA FREDERICK A. MURPHY University of Texas Medical Branch, Texas, USA ADVISORY BOARD DAVID BALTIMORE ROBERT M. CHANOCK PETER C. DOHERTY H. J. GROSS B. D. HARRISON BERNARD MOSS ERLING NORRBY J. J. SKEHEL M. H. V. VAN REGENMORTEL Academic Press is an imprint of Elsevier 32 Jamestown Road, London, NW1 7BY, UK Radarweg 29, PO Box 211, 1000 AE Amsterdam, The Netherlands 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA 525 B Street, Suite 1900, San Diego, CA 92101-4495, USA First edition 2010 Copyright # 2010 Elsevier Inc. All Rights Reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone: (þ44) (0) 1865 843830, fax: (þ44) (0) 1865 853333; e-mail:
[email protected] Alternatively you can submit your request online by visiting the Elsevier web site at http://www.elsevier.com/locate/permissions, and selecting Obtaining permission to use Elsevier material Notice No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library ISBN: 978-0-12-374525-5 ISSN: 0065-3527 For information on all Academic Press publications visit our website at elsevierdirect.com Printed and bound in USA 10 11 12 10 9 8 7 6 5 4 3 2 1 PREFACE We present the second of two volumes of Advances in Virus Research dealing with natural and engineered resistance to plant viruses. Viruses constitute the single largest group of causative agents of emerging and novel plant diseases and thus represent a serious threat to crop production throughout the world. Nevertheless, and as described in our preface to Volume 75, plant viruses also provide an apparently never-ending source of fundamental insights into pathogen and host biology. In this volume, our authors address topics that must be better understood in order to foster