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Lipobiology is an interdisciplinary field which incorporates critical aspects of lipid and lipoprotein chemistry into the disciplines of cell biology and physiology. During the last decade, advances in our understanding of the structure and function of lipids, biological membranes and lipid-derived second messengers have underscored the importance of lipids in the regulation of cellular function. This series focuses on salient aspects of the role of lipids in metabolic regulation and cellular activation, with emphasis on emerging concepts and technologies. One goal of this series is to formulate cohesive criteria upon which a foundation for the evaluation of recent work can be based and future directions of research identified.
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ADVANCES IN LIPOBIOLOGY Volume 7 • 1996 This Page Intentionally Left Blank ADVANCES IN LIPOBIOLOGY Editor: RICHARD W. GROSS Department of Bioorganic Chemistry and Molecular Pharmacology Washington University School of Medicine St Louis, Missouri VOLUME 1 • 1996 UQIJ) JAI PRESS INC. Greenwich, Connecticut London, England Copyright © 1996 byJAI PRESS INC. 55 Old Post Road, No. 2 Greenwich, Connecticut 06836 JAI PRESS LTD. 38 Tavistock Street Covent Garden London, WC2E 7PB England All rights reserved. No part of this publication may be reproduced, stored on a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, filming, recording, or otherwise, without prior permission in writing from the publisher. ISBN: 1-55938-635-5 Manufactured in the United States of America CONTENTS LIST OF CONTRIBUTORS ix PREFACE Richard W. Cross xiii REGULATION OF MAMMALIAN CTP: PHOSPHOCHOLINECYTIDYLYLTRANSFERASE Rosemary B. Cornell 1 INCORPORATION AND TURNOVER OF FATTY ACIDS IN ESCHERICHIA CO/./MEMBRANE PHOSPHOLIPIDS Charles O. Rock and Suzanne Jackowski 39 A BRANCHED METABOLIC PATHWAY IN ANIMAL CELLS CONVERTS 2-MONOACYLGLYCEROL INTO sn-1 -STEAROYL-2-ARACHIDONOYL PHOSPHATIDYLINOSITOL AND OTHER PHOSPHOGLYCERIDES John A. Glomset 61 PROPERTIES AND REGULATION OF MAMMALIAN NONPANCREATIC PHOSPHOLIPASE A2 ENZYMES Christina C. Leslie 101 THE FATE OF PLATELET-ACTIVATING FACTOR: PAF ACETYLHYDROLASES FROM PLASMA AND TISSUES Tada-atsu Imaizumi, Diana M. Stafforini, Yoshiji Yamada, Guy A. Zimmerman, Thomas M. Mclntyre, and Stephen M. Prescott 141 BIOSYNTHESIS OF PLASMALOGENS IN MAMMALIAN CELLS AND THEIR ACCELERATED CATABOLISM DURING CELLULAR ACTIVATION David A. Ford and Richard W. Gross 163 vi PLASMALOGENS, NITROXIDE FREE RADICALS, AND ISCHEMIA-REPERFUSION INJURY IN THE HEART Richard Schuiz PHOSPHOLIPID HYDROLYSIS IN PANCREATIC ISLET BETA CELLS AND THE REGULATION OF INSULIN SECRETION John Turk, Richard W. Gross, and Sasanka Ramanadham THE ROLE OF PAF IN REPRODUCTIVE BIOLOGY Hisashi Narahara, Rene A. Frenkel, and John M. Johnston SPHINGOLIPIDS AS REGULATORS OF CELLULAR GROWTH, DIFFERENTIATION, and BEHAVIOR Alfred H. Merrill, Jr., Dennis C. Liotta, and Ronald T. Riley PHOSPHATIDYLSERINE DYNAMICS AND MEMBRANE BIOGENESIS Pamela J. Trotter and Dennis R. Voelker DIACYLGLYCEROL METABOLISM IN CELLULAR MEMBRANES Rosalind A. Coleman and Steven H. Zeisel PHOSPHATIDYLINOSITOL 4-KINASES IN SACCHAROMYCES CEREVISIAE George M. Carman, Rosa J. Buxeda, and Joseph T. Nickels, Jr. PHOSPHOINOSITIDE METABOLISM IN MYOCARDIAL TISSUE Robert A. Wolf ROLE OF ARACHIDONATE IN MONOCYTE/MACROPHAGE FUNCTION Michelle R. Lennartz and James B. Lefkowith INDEX CONTENTS 193 215 241 273 299 337 367 387 429 463 LIST OF CONTRIBUTORS Rosa J. Buxeda Department of Food Science Rutgers