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Students who take the MRCPsych exams have often found the Basic Sciences component one of the hardest to pass and while it underpins all clinical practice, it will continue to be a large part of the Part II syllabus. Examination Notes in Psychiatry, Second Edition is a thorough and expanded revision guide that has helped many trainees tackle difficult subjects, such as Psychological Assessment, Psychopharmacology and Neuroimaging. All the material has been reviewed in the light of college recommendations and the changes to the syllabus, and the book now covers every subject in a succinct, easily absorbable style.
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Examination Notes in Psychiatry BASIC SCIENCES
2nd edition GIN S. MALHI MBChB BSc(Hons) MRCPsych FRANZCP School of Psychiatry, University of New South Wales, Sydney, Australia SAJ MALHI MBChB MRCPsych South Kensington and Chelsea Mental Health Centre, London, UK
Hodder Arnold A MEMBER OF THE HODDER HEADLINE GROUP LONDON
First published in Great Britain in 1999 by Butterworth Heinemann This second edition published in 2006 by Hodder Arnold, an imprint of Hodder Education and a member of the Hodder Headline Group, 338 Euston Road, London NW1 3BH http://www.hoddereducation.com Distributed in the United States of America by Oxford University Press Inc., 198 Madison Avenue, New York, NY10016 Oxford is a registered trademark of Oxford University Press © 2006 Gin S. Malhi and Saj Malhi All rights reserved. Apart from any use permitted under UK copyright law, this publication may only be reproduced, stored or transmitted, in any form, or by any means with prior permission in writing of the publishers or in the case of reprographic production in accordance with the terms of licences issued by the Copyright Licensing Agency. In the United Kingdom such licences are issued by the Copyright Licensing Agency: 90 Tottenham Court Road, London W1T 4LP Whilst the advice and information in this book are believed to be true and accurate at the date of going to press, neither the author[s] nor the publisher can accept any legal responsibility or liability for any errors or omissions that may be made. In particular (but without limiting the generality of the preceding disclaimer) every effort has been made to check drug dosages; however it is still possible that errors have been missed. Furthermore, dosage schedules are constantly being revised and new side-effects recognized. For these reasons the reader is strongly urged to consult the drug companies’ printed instructions before administering any of the drugs recommended in this book. British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging-in-Publication Data A catalog record for this book is available from the Library of Congress ISBN-10 ISBN-13
0 340 815 736 978 0 340 815 731
1 2 3 4 5 6 7 8 9 10 Commissioning Editor: Clare Christian Project Editor: Clare Patterson Production Controller: Jane Lawrence Cover Designer: Nichola Smith Typeset in 9/11 Minion by Charon Tec Pvt. Ltd, Chennai, India www. charontec.com Printed and bound in Malta
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Contents Preface Acknowledgements 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
ix xi
Basic psychology Social psychology Neuropsychology Psychological assessment Human development Social sciences Important theorists and their concepts Psychopathology Neuroanatomy Neurology Neuropathology Neurophysiology Neurochemistry Psychopharmacology Genetics Neuroimaging Peptidergic neurotransmission and neuroendocrinology Statistics
1 14 24 31 38 52 57 70 83 94 115 123 136 154 184 202 207 216
Appendices References and further reading Index