Nitric Oxide Synthase Characterization And Functional Analysis

Nitric Oxide Synthase: Characterization and Functional Analysis This Page Intentionally Left Blank Nitric Oxide Synthase: Characterization and Functional Analysis Edited by Mahin D. Maines Department of Biophysics University of Rochester Medical Center Rochester, New York ACADEMIC PRESS San Diego London Boston New York Sydney Tokyo Toronto Front cover photograph: Cortical neurons. This book is printed on acid-free paper. @ Copyright 0 1996 by ACADEMIC PRESS All Rights Reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Academic Press, Inc. 525 B Street, Suite 1900, San Diego, California 92101-4495, USA http://www.apnet.com Academic Press Limited 24-28 Oval Road, London NW1 7DX, UK http://www.hbuk.co.uk/ap/ International Standard Serial Number: 1043-947 1 International Standard Book Number: 0-12-185301-2 PRINTED IN THE UNITED STATES OF AMERICA 96 97 9 8 9 9 00 0 1 E B 9 8 7 6 5 4 3 2 1 Table of Contents Contributors Preface Volumes in Series ix xv xvii Section I Enzyme Activity Measurements, Nitric Oxide Detection, and Tissue Localization 1. Electron Paramagnetic Resonance Detection of Nitric Oxide in Biological Samples 3 Lori G . Rochelle, Harriet Kruszyna, and Roger P. Smith 2. Electrochemical and Spectroscopic Methods of Nitric Oxide Detection 14 Tadeusz Malinski, Eugeniusz Kubaszewski, and Frederick Kiechle 3. Detection of S-Nitrosothiols 34 George N . Welch, Gilbert R . Upchurch, Jr., and Joseph Loscalzo 4. Nitrosation of Proteins 41 Yi