Recent Advances In Predicting And Preventing Epileptic Seizures

Recent Advances in Predicting and Preventing Epileptic Seizures 8886_9789814525343_tp.indd 1 10/7/13 4:46 PM This page intentionally left blank Recent Advances in Predicting and Preventing Epileptic Seizures edited by Ronald Tetzlaff Technische Universität Dresden, Germany Christian E. Elger Universitätsklinikum Bonn, Germany Klaus Lehnertz Universitätsklinikum Bonn, Germany World Scientific NEW JERSEY • LONDON 8886_9789814525343_tp.indd 2 • SINGAPORE • BEIJING • SHANGHAI • HONG KONG • TA I P E I • CHENNAI 10/7/13 4:46 PM Published by World Scientific Publishing Co. Pte. Ltd. 5 Toh Tuck Link, Singapore 596224 USA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601 UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library. RECENT ADVANCES IN PREDICTING AND PREVENTING EPILEPTIC SEIZURES Proceedings of the 5th International Workshop on Seizure Prediction Copyright © 2013 by World Scientific Publishing Co. Pte. Ltd. All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the Publisher. For photocopying of material in this volume, please pay a copying fee through the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to photocopy is not required from the publisher. ISBN 978-981-4525-34-3 Printed in Singapore June 20, 2013 9:47 WSPC - Proceedings Trim Size: 9in x 6in 07-rothkegel Preface This book comprises contributions delivered at the 5th International Workshop on Seizure Prediction held in Dresden, Germany in the September of 2011. This workshop followed a series of international meetings on seizure prediction, seizure dynamics, and seizure control hosted in Bonn in 2002, Bethesda in 2006, Freiburg in 2007, and Kansas City in 2009. This series proved highly successful in bringing together specialists from a wide range of backgrounds - including epileptology, neurosurgery, neurosciences, physics, mathematics, computer science, and engineering - that are engaged in improving our understanding of mechanisms leading to seizures in humans and in developing new therapeutic options. The workshop covered topics such as recent approaches to seizure control, recent developments in signal processing of interest for seizure prediction, ictogenesis in complex epileptic brain networks, active probing of the pre-seizure state, non-EEG based approaches to the transition to seizures, microseizures and their role in the generation of clinical seizures, the impact of sleep and longbiological cycles on seizure prediction, as well as animal and computational models of seizures and epilepsy. Furthermore the workshop program covered recent developments