E-Book Overview
This reference provides a review of enzyme functions in human and animal health. It covers basic principles and applications in antibiotic biosynthesis, biocatalysis, and screening and assay optimization, as well as new and emerging technologies in the biotechnological and pharmaceutical industries. Emphasizing modern methods of metabolic engineering and drug discovery processes, the book details enzyme targets related to human disease. It also discusses effective enzymatic assays, high-throughput screening, novel compounds for lead generation, improvements in antibiotic yield, and the generation of contemporary protein products.
E-Book Content
ISBN: 0-8247-0549-1 This book is printed on acid-free paper. Headquarters Marcel Dekker, Inc. 270 Madison Avenue, New York, NY 10016 tel: 212-696-9000; fax: 212-685-4540 Eastern Hemisphere Distribution Marcel Dekker AG Hutgasse 4, Postfach 812, CH-4001 Basel, Switzerland tel: 41-61-261-8482; fax: 41-61-261-8896 World Wide Web http:/ /www.dekker.com The publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales/Professional Marketing at the headquarters address above. Copyright 2001 by Marcel Dekker, Inc. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher. Current printing (last digit): 10 9 8 7 6 5 4 3 2 1 PRINTED IN THE UNITED STATES OF AMERICA
Preface
Genes related to human and animal health are being discovered at an ever-increasing rate. As gene products, enzymes are being explored for their function and application in a rapidly emerging field that has been termed functional genomics. Enzyme Technologies for Pharm