The Chemistry Of Mood, Motivation, And Memory: The Proceedings Of An Interdisciplinary Conference On The Chemistry Of Mood, Motivation, And Memory Held At The University Of California, San Francisco, In October 1971

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This volume is based on presentations at an interdisciplinary conference on The Chemistry of Mood, Motivation and Memory which was held at the University of California, San Francisco in October, 1971. The conference was sponsored and supported by the Division of Continuing Education in Health Sciences. We thank Dr. Ruben Dixon and his staff for help in planning the conference and for attending to all of the organizational details. We particularly thank the participants for their contributions to the conference and for their cooperation in preparing the manu­ scripts based on their conference presentations. All of the details involved in preparing the volume for publi­ cation were handled by Karen Dodd. We are grateful to her for her tireless, efficient and productive efforts. We hope that this volume will help to stimulate further interest as well as understanding of the biochemical bases of our behavior. James L. McGaugh v CONTRIBUTORS Bernard W. Agranoff, Ph.D. Department of Psychiatry Mental Health Research Institute The University of Michigan Ann Arbor, Michigan Samuel H. Barondes, M.D. Professor of Psychiatry School of Medicine University of California at San Diego La Jolla, California Barry D. Berger, Ph.D. Wyeth Laboratories Philadelphia, Pennsylvania Enoch Callaway, M.D. Professor of Psychiatry University of California School of Medicine San Francisco, California J. Anthony Deutsch, Ph.D. Professor of Psychology University of California at San Diego La Jolla, California Edward Glassman, Ph.D.


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THE CHEMISTRY OF MODO. MOTIVATION. AND MEMORY ADVANCES IN BEHAVIORAL BIOLOGY Editorial Board: Jan Bures Institute of Physiology, Prague, Czechoslovakia Irwin Kopin Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, Maryland Bruce McEwen Department of Biology, Rockefeller University, New York, New York James McGaugh Department of Psychobiology, University of California, Irvine, California Karl Pribram Department of Psychology, Jordan Hall, Stanford University School of Medicine, Stanford, California Jay Rosenblatt Institute of Animal Behavior, Rutgers University, Newark, New Jersey Lawrence Weiskrantz Institute of Experimental Psychology, University of Oxford, Oxford, England Volume 1 • BRAIN CHEMISTRY AND MENTAL DISEASE Edited by Beng T. Ho and William M. Mcisaac' 1971 Volume 2 • NEUROBIOLOGY OF THE AMYGDALA Edited by Basil E. Eleftheriou. 1972 Volume 3 • AGING AND THE BRAIN Edited by Charles M. Gaitz· 1972 Volume 4 • THE CHEMISTRY OF MOOD, MOTIVATION, AND MEMORY Edited by James L. McGaugh • 1972 THE CHEMISTRY OF MOOD. MOTIVATION. AND MEMORY The proceedings of an interdisciplinary conference on the Chemistryof Mood, Motivation, and Memory held at the University of California, San Francisco, in October 1971 EDITED BY JAMES L. McGAUGH Department of Psychobiology School of Biological Sciences University of California, Irvine Irvine, California ~ PLENUM PRESS • NEW YORK-LONDON • 1872 ISBN-13: 978-1-4684-3062-2 e-ISBN-13: 978-1-4684-3060-8 DOl: 10.1007/978-1-4684-3060-8 Library of Congress Catalog Card Number 72-83801 © 1972 Plenum Press, New York Softcover reprint of the hardcover 1st edition 1972 A Division of Plenum Publishing Corporation 227 West 17th Street, New York, N. Y. 10011 United Kingdom edition published by Plenum Press, London A Division of Plenum Publishing Company, Ltd. Davis House (4th Floor), 8 Scrubs Lane, Harlesden, London, NW10 6SE, England All rights reserved No part of this publication may be reproduced in any form without written permission from the publisher PREFACE This volume is based on presentations at an interdisciplinary conference on The
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